Local Buckling Check and Sensitivity Analysis Based on J-lay
Shiyou jixie, 2018 In view of the limitation of the local buckling failure evaluation formula of J-lay based on the natural catenary model, the Winkler foundation modeling is introduced for improvement. The entire suspension section is divided into two sections.
Wang Shuai
doaj
Space shuttle SRM plume expansion sensitivity analysis [PDF]
The exhaust plumes of the space shuttle solid rocket motors can have a significant effect on the base pressure and base drag of the shuttle vehicle. A parametric analysis was conducted to assess the sensitivity of the initial plume expansion angle of ...
Penny, M. M. +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
SACR EPIDEMIC MODEL FOR THE SPREAD OF HEPATITIS B DISEASE BY CONSIDERING VERTICAL TRANSMISSION
BarekengHepatitis B is an infectious disease that causes inflammation of the liver due to infection with the Hepatitis B virus. Hepatitis B is divided into two phases: the acute phase and the chronic phase.
Yuni Yulida +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Non-Local Sensitivity Analysis and Numerical Homogenization in Optimal Design of Single-Wall Corrugated Board Packaging. [PDF]
Materials (Basel), 2022 Mrówczyński D +2 more
europepmc +1 more source
An Investigation of Successful and Unsuccessful Communication between International and North African Social Workers at Centres for Disabled Children in North Africa [PDF]
, 2011 There is a need to improve the quality of life for disabled children in North Africa. Although local governments and communities have been providing social services support, an increase in social services investment, particularly, specialists who work in
Okuyama, Yusuke
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source