Results 61 to 70 of about 2,723,865 (337)

Experimental observation of hidden Berry curvature in inversion-symmetric bulk 2H-WSe2 [PDF]

open access: yes, 2017
We investigate the hidden Berry curvature in bulk 2H-WSe2 by utilizing the surface sensitivity of angle resolved photoemission (ARPES). The symmetry in the electronic structure of transition metal dichalcogenides is used to uniquely determine the local ...
Cho, Soohyun   +13 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

No. 09: Comparing Household Food Security in Cities of the Global South through a Gender Lens [PDF]

open access: yes, 2017
Understanding the determinants of urban food insecurity requires sensitivity to local cultural contexts and taking into account a globally relevant framework for analysis.
Caesar, Mary, Riley, Liam
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Differential and Time-Discrete SEIRS Models with Vaccination: Local Stability, Validation and Sensitivity Analysis Using Bulgarian COVID-19 Data

open access: yesMathematics, 2023
Bulgaria has the lowest COVID-19 vaccination rate in the European Union and the second-highest COVID-19 mortality rate in the world. That is why we think it is important better to understand the reason for this situation and to analyse the development of
Svetozar Margenov   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Local and global sensitivity analysis for railway upgrading between hydrogen fuel cell and electrification

open access: yesHigh-Speed Railway
In the field of rail transit, the UK Department of Transport stated that it will realize a comprehensive transformation of UK railways by 2050, abandoning traditional diesel trains and upgrading them to new environmentally friendly trains.
Yizhe Zhang   +4 more
doaj   +1 more source

SBML-SAT: a systems biology markup language (SBML) based sensitivity analysis tool

open access: yesBMC Bioinformatics, 2008
Background It has long been recognized that sensitivity analysis plays a key role in modeling and analyzing cellular and biochemical processes. Systems biology markup language (SBML) has become a well-known platform for coding and sharing mathematical ...
Rundell Ann E   +3 more
doaj   +1 more source

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