Results 101 to 110 of about 87,777 (313)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Building Transit Ridership: An Exploration of Transit\u27s Market Share and the Public Policies That Influence It [PDF]
, 1997 TRB\u27s Transit Cooperative Research Program (TCRP) Report 27: Building Transit Ridership: An Exploration of Transit\u27s Market Share and the Public Policies That Influence It addresses transit\u27s ridership and its share of the travel market.
Transportation Research Board +1 more
core
PLoS ONE, 2015 OBJECTIVE:Several ultrasound-based methods are currently used to assess aortic diameter, circumferential strain and stiffness in mice, but none of them is flawless and a gold standard is lacking.
Bram Trachet +5 more
doaj +1 more source
Energy accounting in AC substations in case of transit currents flowing through the contact network
Вестник Научно-исследовательского института железнодорожного транспорта, 2017 The purpose of the work is to clarify the methodology for determining the electric power consumption of traction substations of AC electric power for the transit of external power supply.
V. M. Varentsov +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Costs and Technology of Public Transit Systems in Italy:Some Insights to Face Inefficiency [PDF]
This study provides fresh evidence about the characteristics of technology and cost structure of public transit systems in Italy. The aim is to suggest useful guidelines for facing detected inefficiencies.
Graziano Abrate +2 more
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Evaluation of Transit Signal Priority Using Observed and Simulated Data [PDF]
, 2009 The South Snohomish Regional Transit System Priority (SS-RTSP) system was launched in Washington state to improve the level of service for community transit buses.
Zheng, Jianyang +3 more
core
Optimization for Express/Local Train Stop Plans on City Rapid Rail Transit Lines
Chengshi guidao jiaotong yanjiu[Objective] To minimize passenger travel time while reducing operational costs for enterprises, it is necessary to identify an optimal balance between these two competing objectives.
GUO Jingfan
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source