Results 81 to 90 of about 87,777 (313)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Public Transit Investment Decisions: Per capita trends and conditions [PDF]
, 2001 The paper reviews the history of public transit back to 1954 when the Interstate Highway System first was initiated, a system that received major federal investments, along with the mass production of affordable automobiles, making it near impossible for
Center for Urban Transportation Research
core
Applying data science to analyze internal trip capture for station area neighborhoods
Journal of Urban MobilityLocal accessibility, or accessibility by proximity, is a planning priority that is increasingly discussed within the context of the 15-Minute City. The goal of local accessibility is both to facilitate residents’ quality of life and to promote more ...
Louis A. Merlin +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Social Transit as Mass Transit in Australian Suburban Greenfield Development [PDF]
, 2016 The operation of public transport service in suburban developments, particularly new greenfield developments, can face considerable challenges. Suburban developments are often served primarily through bus transit, which struggles to balance a mass ...
Delbosc, Alexa +3 more
core +1 more source
Localism and the Transition movement
Policy Studies, 2013 This article explores the relationship between localism and contemporary community engagement. In particular, it focuses on the Transition movement, an especially interesting case, given its localistic and community-oriented nature. The article begins with a short discussion of more traditional conceptions of localism.
openaire +4 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
What the heck is a choice rider? A theoretical framework and empirical model
Journal of Transport and Land Use, 2022 As local, state, and federal agencies began investing substantial resources into subsidizing transit in the 1960s and ‘70s, public documents argued that transit agencies should focus on attracting choice riders instead of dependent riders, who have no ...
Erick Guerra
doaj
Locally s -distance transitive graphs and pairwise transitive designs
Journal of Combinatorial Theory, Series A, 2013 22 pages, has been accepted for publication in J. Comb.
Alice Devillers +3 more
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source