Results 81 to 90 of about 1,518,582 (299)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Idioms reflecting the interplay between cognition and emotion in cognitive behavioral therapy

Sichuan jingshen weisheng
BackgroundCognitive behavioral therapy （CBT） is a widely used and empirically supported psychotherapy method. In recent years， the localization of CBT related to culture has received increasing attention from Chinese scholars.
Xu Jingren, Yang Hua, Lin Chenchen, Liu Na, Ma Hui, Pei Tao, Hu Mingyu, Zhang Ning   +7 more
doaj   +1 more source

Localized lichen myxedematosus [PDF]

, 2020
INSERM
openalex   +1 more source

Localized Complications from Local Anesthesia

Journal of the California Dental Association, 1998
The inherent safety of local anesthetics allows practitioners to use them frequently with the confidence that adverse events are rare. Nevertheless, complications can occur. The aim of this article is to briefly review the localized adverse events that may result from local anesthetic administration.
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A Model for the Identification and Evaluation of Locations of Agencies and Branches of Service – Industrial Companies [PDF]

چشم‌انداز مدیریت صنعتی, 2013
One of the factors affecting the efficiency and effectiveness of a bank is its location. An optimal location for the establishment of a branch can pave the way to meet other bank objectives.
Farhad Farzad, Morteza Maddah, Amir Zarkar   +2 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Detection and Localization of Stationary Waves on Venus Using a Self‐Supervised Anomaly Detection Model

Journal of Geophysical Research: Machine Learning and Computation
The atmosphere of Venus features stationary waves of planetary scale, which are believed to be caused by wind flowing over elevated terrains. Detecting these waves can provide valuable insight into atmospheric dynamics.
Husnu Baris Baydargil, Jose Eduardo Oliveira Silva, Yeon Joo Lee, Meeyoung Cha   +3 more
doaj   +1 more source

Magnetic Source Detection Using an Array of Planar Hall Effect Sensors and Machine Learning Algorithms

Applied Sciences
We use an array of nine elliptical Planar Hall Effect (PHE) sensors and machine learning algorithms to map the magnetic signal generated by a magnetic source. Based on the obtained mapping, the location and nature of the magnetic source can be determined.
Miki Vizel, Roger Alimi, Daniel Lahav, Moty Schultz, Asaf Grosz, Lior Klein   +5 more
doaj   +1 more source