Results 311 to 320 of about 4,204,651 (354)

LOCALLY ADVANCED BREAST CANCER

Hematology/Oncology Clinics of North America, 1999
The multidisciplinary management of patients with locally advanced breast cancer (LABC) has evolved over the last three decades. The introduction of chemotherapy (CT) and endocrine therapy in conjunction with surgery and radiation therapy (XRT) have changed the natural history of this disease.
F J, Esteva, G N, Hortobagyi
openaire   +2 more sources

Neoadjuvant and Adjuvant Pembrolizumab in Locally Advanced Head and Neck Cancer.

New England Journal of Medicine
BACKGROUND The benefit of the addition of perioperative pembrolizumab to standard care with surgery and adjuvant therapy for patients with locally advanced head and neck squamous-cell carcinoma (HNSCC) is unclear.
R. Uppaluri, R. I. Haddad, Y. Tao, C. Le tourneau, Nancy Y. Lee, W. Westra, R. Chernock, Makoto Tahara, Kevin J. Harrington, A. Klochikhin, I. Braña, Gustavo Vasconcelos Alves, B. Hughes, M. Oliva, Iane Pinto Figueiredo Lima, Tsutomu Ueda, Tomasz Rutkowski, Ursula Schroeder, P. Mauz, T. Fuereder, S. Laban, N. Oridate, Aron Popovtzer, Nicolas Mach, Yevhen Korobko, D. A. Costa, A. Hooda-Nehra, Cristina P. Rodriguez, R. B. Bell, C. Manschot, K. Benjamin, B. Gumuscu, D. Adkins   +32 more
semanticscholar   +1 more source

Locally advanced nasopharyngeal cancer

Current Treatment Options in Oncology, 2001
The Head and Neck Cancer Intergroup phase III clinical trial (Int 0099) for patients with locally advanced, squamous cell carcinomas (SCC) of the nasopharynx (or NPC) has been recently completed in the United States. The results of this study have defined the new standard of treatment for the group of patients studied.
J F, Ensley, E, Youssef, H, Kim, G, Yoo
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Durvalumab and tremelimumab with definitive chemoradiotherapy for locally advanced esophageal squamous cell carcinoma

Cancer, 2022
The current standard treatment for patients with inoperable, locally advanced esophageal squamous cell carcinoma (ESCC) is definitive concurrent chemoradiotherapy (CCRT).
Sehhoon Park, D. Oh, Yoon-La Choi, S. Chi, K. Kim, M. Ahn, Jong-Mu Sun   +6 more
semanticscholar   +1 more source

Pembrolizumab or Placebo With Chemoradiotherapy Followed by Pembrolizumab or Placebo for Newly Diagnosed, High-Risk, Locally Advanced Cervical Cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): A Randomized, Double-Blind, Phase 3 Clinical Trial

Obstetrical & Gynecological Survey
(Abstracted from Lancet 2024;403:1341–1350) Prognosis for locally advanced cervical cancer is poor, with 5-year progression-free survival (PFS) and overall survival ranging from 47% to 80%.
Domenica Lorusso, Y. Xiang, K. Hasegawa, G. Scambia, Manuel Leiva, Pier Ramos-Elias, A. Acevedo, V. Sukhin, N. Cloven, A. J. Pereira de Santana Gomes, F. C. Mejía, A. Reiss, Ali Ayhan, Jung-Yun Lee, V. Saevets, F. Zagouri, Lucy Gilbert, J. Sehouli, E. Tharavichitkul, Kristina Lindemann, R. Lazzari, Chi-Long Chang, Rudolf Lampé, Hong Zhu, A. Oaknin, Melissa Christiaens, S. Polterauer, T. Usami, Kan Li, K. Yamada, S. Toker, Steve Keefe, Sandro Pignata, L. Duska   +33 more
semanticscholar   +1 more source

Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial.

Annals of Oncology
BACKGROUND The standard of care for the treatment of locally advanced rectal cancer results in an excellent local disease control but the metastasis rates remain high.
T. Conroy, F. Castan, P. Etienne, E. Rio, N. Mesgouez-Nebout, L. Evesque, V. Vendrely, X. Artignan, O. Bouché, D. Gargot, V. Boige, N. Bonichon-Lamichhane, C. Louvet, C. Morand, C. de la Fouchardière, A. Boilève, M. Delaye, S. Gourgou, V. Pezzella, C. Borg   +19 more
semanticscholar   +1 more source

Locally Advanced Thyroid Carcinoma

Annals of Otology, Rhinology & Laryngology, 2004
Patients with locally advanced thyroid carcinoma were studied to document survival, posttreatment vocal cord function, and dysphagia. A retrospective medical record review collected patient data recorded, including age, gender, and tumor-specific data.
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Management of Locally Advanced Rectal Cancer: ASCO Guideline

Journal of Clinical Oncology
ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following the guideline development process as outlined in the ASCO Guidelines Methodology Manual.
MD Aaron J. Scott, MHSc Erin B. Kennedy, MD Jordan Berlin, Mbbs Gina Brown, MD PhD Myriam Chalabi, MD May T. Cho, MD Mike Cusnir, MD Jennifer Dorth, Dvm PhD Manju George, MD Lisa A. Kachnic, MD Hagen F. Kennecke, MD Jonathan M. Loree, MD Van K. Morris, Rodrigo, MD PhD Oliva Perez, MD PhD J. Joshua Smith, MD Matthew R. Strickland, MD Mas Sepideh Gholami   +17 more
semanticscholar   +1 more source

Locally advanced breast cancer

Current Treatment Options in Oncology, 2000
Over the past 20 years, the prognosis for women diagnosed with locally advanced breast cancer (LABC; clinical stages IIB through IIIB) has improved significantly with recognition of the efficacy of multimodal therapy for reducing both local and distant recurrences, even in patients with inflammatory breast cancer (IBC).
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Locally advanced cervical cancer

Current Opinion in Obstetrics and Gynecology, 2001
Cervical cancer is a tremendous health problem as the third most frequent cancer affecting women. Locally advanced disease, which exceeds that successfully treated with surgery, is a common presentation of unscreened women. The use of concurrent chemotherapy and radiation therapy has resulted in a significant increase in patient survival.
openaire   +2 more sources