Results 21 to 30 of about 8,380,026 (270)

Sonidegib treatment in patients with locally advanced basal cell carcinoma. [PDF]

Dermatol Ther, 2022
Villani A, Fabbrocini G, Scalvenzi M.
europepmc   +5 more sources

Sonidegib in Locally Advanced Basal Cell Carcinoma: A Monocentric Retrospective Experience and a Review of Published Real-Life Data. [PDF]

Cancers (Basel), 2023
Nazzaro G, Benzecry V, Mattioli MA, Denaro N, Beltramini GA, Marzano AV, Passoni E.   +6 more
europepmc   +2 more sources

Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma

, 2022
Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell ...
Nicole Basset-Seguin (187601), Florian Herms (15045215), Nicolas Meyer (86532), Caroline Dutriaux (15033126), Andrey A. Yurchenko (15045188), Fanny Bouquet (15045206), Brigitte Dreno (292705), Fatemeh Rajabi (691876), Sergey I. Nikolaev (14909870), Florent Grange (3569189), Caroline Robert (15032672), Lukas Flatz (251190), Meriem Ighilahriz (15045194), Oltin T. Pop (15045191), Samia Mourah (15033147), Sandrine Monestier (15045212), Nicolas Dumaz (365666), Frederic J. de Sauvage (15045218), Nicolas Poulalhon (15045200), Andrej Besse (2899043), Jerome Lambert (282171), Marc Delord (12064068), Antonio Alberti (15045203), Ariel Savina (3157380), Philippe Saiag (4219240), Max Mendez-Lopez (15045209), Nadem Soufir (108407), Maxime Battistella (15033144), Hayley J. Sharpe (15045197), Ismael Padioleau (687518), Laurent Mortier (4030046), Amir Khammari (149729)   +31 more
core   +8 more sources

Locally advanced basal cell carcinoma of the auricle and parotid region: A case report [PDF]

Stomatološki glasnik Srbije, 2021
Skin cancers are the most common malignant tumors in general. The most significant risk factor is exposure to UV radiation. They mainly occur in the head and neck region, and the majority of about 80% are basal cell carcinomas.
Milanović Srđan, Stojanović-Rundić Suzana, Milošević Nikola, Dožić Branko, Dožić Marko   +4 more
doaj   +1 more source

Sonidegib in the Treatment of Locally Advanced Basal Cell Carcinoma

Actas Dermo-Sifiliográficas (English Edition), 2021
Sonidegib is an antagonist of the transmembrane protein Smoothened in the Hedgehog signaling pathway. It is indicated for the treatment of locally advanced basal cell carcinoma (BCC) that is not amenable to curative surgery or radiotherapy. Sonidegib's efficacy and safety were demonstrated in the phase 2 BOLT trial, where 61% (95% CI, 48-72%) of ...
Sanmartín, O, Llombart, B, Carretero Hernández, G, Flórez Menéndez, Á, Botella-Estrada, R, Herrera Ceballos, E, Puig, S   +6 more
openaire   +5 more sources

Treatment of periocular advanced basal cell carcinoma with Hedgehog pathway inhibitors: a single-center study and a new dedicated therapeutic protocol

Dermatology Reports, 2021
Background: The management of difficult-to-treat periocular basal cell carcinoma becomes very challenging in cases of delayed diagnosis, leading to the development of locally advanced basal cell carcinoma. Objective: The aim of this study was to evaluate
Vincenzo De Giorgi, Luciana Trane, Giulia Pieretti, Nicola Santoro, Flavia Silvestri , Federico Venturi, Federica Scarfi, Vincenza Maio, Giuseppe Spinelli, Silvia Scoccianti, Laura Guerrini, Daniela Massi, Cinzia Mazzini, Laura Doni   +13 more
doaj   +1 more source

Locally Advanced Basal Cell Carcinoma with Intraocular Invasion. [PDF]

Open Access Maced J Med Sci, 2018
We present a 103 - year - old patient, with duration of complaints of about ten years. The initial complaint had been presented as a small nodule, located on the eyebrow, which subsequently ulcerated and encompassed larger regions of the upper and lower eyelids.
Tchernev G, Lotti T, Lozev I, Maximov GK, Wollina U.   +4 more
europepmc   +4 more sources

Vismodegib y sonidegib en el carcinoma de células basales localmente avanzado y metastásico: actualización acerca de los inhibidores de la vía de Hedgehog

Actas Dermo-Sifiliográficas, 2022
Resumen: El carcinoma de células basales (CBC) es una de las neoplasias malignas más frecuentes, por lo que se ha convertido en una importante carga asistencial. Su incidencia se incrementa anualmente, especialmente en la población con mayor edad.
J. Kurnia Wijaya, K. Djawad, S. Wahab, A. Nurdin, A. Irawan Anwar   +4 more
doaj   +1 more source

Vismodegib for treatment of periocular basal cell carcinoma – 6-year experience from a tertiary cancer center, [PDF]

Anais Brasileiros de Dermatologia, 2022
Background: The treatment of advanced periocular basal cell carcinomas becomes a challenge as surgery may involve highly mutilating procedures. Vismodegib is the first selective hedgehog inhibitor approved for the treatment of locally advanced tumors or ...
Catarina Xavier, Edgar Lopes, Catarina Bexiga, Cecília Moura, Emanuel Gouveia, Ana Filipa Duarte   +5 more
doaj   +1 more source

Determination of locally advanced basal cell carcinoma in patients in Cohort 1.

, 2022
Determination of locally advanced basal cell carcinoma in patients in Cohort 1.
Simon Yoo (11949194), Aleksandar Sekulic (3192720), Laura Chu (1891477), Edward McKenna (4030052), Yong Mun (9200749), Julie Guillen (11949200), Ragini Kudchadkar (11949197), Gary Rogers (505210), Keith Dawson (11949209), Scott Guenthner (11949203), Mario Lacouture (11949212), Anne Lynn S. Chang (3339900), Bernard Raskin (11949206)   +12 more
core   +1 more source