Results 41 to 50 of about 8,380,026 (270)

Experience with sonidegib in patients with advanced basal cell carcinoma: case reports

open access: yesDrugs in Context, 2022
Sonidegib is a Hedgehog signalling pathway inhibitor approved for use in patients with advanced basal cell carcinoma (BCC) not eligible for surgery or radiotherapy.
Susana Puig   +4 more
doaj   +1 more source

Treatment of periocular basal cell carcinoma with neoadjuvant vismodegib

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: To report a case of a locally advanced periocular basal cell carcinoma treated with neoadjuvant Vismodegib therapy prior to surgery. Observations: A 63-year-old female presented to the oculoplastics clinic with biopsy-proven basal cell carcinoma
Maxwell G. Su   +2 more
doaj   +1 more source

Gefitinib and Radiotherapy in patients with locally advanced inoperable squamous cell carcinoma of the head and neck [PDF]

open access: yes, 2008
Introduction: Gefitinib, an orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces growth arrest in squamous cancer cell carcinoma of head and neck (SCCHN) cell lines mainly by blocking cells in G1 and preventing them ...
Romano, Carmela
core   +1 more source

Tolerance of sonidegib after intolerance of vismodegib—Experience in two patients with nevoid basal cell carcinoma syndrome (Gorlin syndrome)

open access: yesSkin Health and Disease, 2023
Nevoid basal cell carcinoma syndrome (NBCCS, Gorlin syndrome) is a rare genetic condition characterized by the early development of numerous cutaneous basal cell carcinomas (BCCs).
Federico Venturi   +5 more
doaj   +1 more source

The role of GLI2 in human basal cell carcinoma tumourigenesis [PDF]

open access: yes, 2010
PhDAbnormal Sonic Hedgehog (SHH) signalling leads to increased transcriptional activation of its downstream effector, GLI2, which is implicated in the pathogenesis of a variety of human tumours, including human basal cell carcinoma (BCC).
Pantazi, Eleni
core   +2 more sources

Prostatic basal cell carcinoma treated by chemoradiation with weekly cisplatine: case report and literature review

open access: yesAfrican Journal of Urology, 2021
Background Basal cell carcinoma of the prostate is a relatively rare entity. Their evolution is characterized by the frequency of local and/or distant relapses. Due to their rarity, the treatment is not consensual in the literature. We report here a case
S. Ridai   +6 more
doaj   +1 more source

Vismodegib for Locally Advanced Basal Cell Carcinoma in a Heart Transplant Patient [PDF]

open access: yesJAMA Dermatology, 2015
Immunosuppressed patients with solid organ transplants have an increased risk for nonmelanoma skin cancer. Vismodegib has been reported to be effective for select locally advanced or metastatic basal cell carcinomas. However, there is no data documenting the use and safety of vismodegib in immunosuppressed organ transplant patients.We describe a 78 ...
Carrie Ann, Cusack   +6 more
openaire   +2 more sources

Brief overview: cemiplimab for the treatment of advanced basal cell carcinoma: PD-1 strikes again

open access: yesTherapeutic Advances in Medical Oncology, 2022
Basal cell carcinoma (BCC) is the most common malignancy worldwide. Fortunately, most tumors are localized and easily amenable to surgical resection or locally destructive treatments.
Christina M. Davis, Karl D. Lewis
doaj   +1 more source

Lasting response after discontinuation of cemiplimab in a patient with locally advanced basal cell carcinoma

open access: yes, 2021
Lasting response after discontinuation of cemiplimab in a patient with locally advanced basal cell ...
Scarfi F.   +13 more
core   +1 more source

Periocular basal cell carcinoma with orbital invasion: a case report [PDF]

open access: yesSurgical & Cosmetic Dermatology
Basal cell carcinoma is the most frequent periocular neoplasm. Although mortality is low, orbital invasion represents a severe complication associated with high morbidity.
Mariana Sofia Monteiro Silva   +4 more
doaj   +1 more source

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