Results 61 to 70 of about 8,380,026 (270)

Vismodegib: A smoothened inhibitor for the treatment of advanced basal cell carcinoma

Indian Dermatology Online Journal, 2013
Incidence of basal cell carcinoma (BCC), the most common skin cancer in humans, is rising. Surgery is the mainstay of treatment but there is no standard of care for locally advanced or metastatic disease. Hedgehog signaling proteins are critical for cell
Suruchi Aditya, Aditya Rattan
doaj   +1 more source

Sonidegib en el tratamiento del carcinoma basocelular localmente avanzado

Actas Dermo-Sifiliográficas, 2021
Resumen: Sonidegib es un inhibidor del receptor transmembrana Smoothened (SMO), de la vía de señalización de Hedgehog, indicado para el tratamiento del carcinoma basocelular localmente avanzado (CBCla), no susceptible a cirugía curativa ni a radioterapia.
O. Sanmartín, B. Llombart, G. Carretero Hernández, Á. Flórez Menéndez, R. Botella-Estrada, E. Herrera Ceballos, S. Puig   +6 more
doaj   +1 more source

Reflectance Confocal Microscopy Identification of Subclinical Basal Cell Carcinoma after Vismodegib Treatment: Report of a Case

, 2021
Although surgery represents the treatment of choice for the majority of basal cell carcinomas, different therapies are required to treat the advanced ones.
Fabbrocini G., Villani A., Scalvenzi M., Costa C., Gabriella Fabbrocini, Claudia Costa, Alessia Villani, Massimiliano Scalvenzi   +7 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Maxillary plexiform ameloblastoma showing basaloid differentiation: Report of a rare case with review of literature

Indian Journal of Dental Research, 2015
Ameloblastoma is a benign, locally aggressive tumor originating from the odontogenic epithelium. It manifests as a slow growing swelling, causing expansion of the jaw bones.
Sravani Ghattamaneni, Venkateswara Rao Guttikonda, M Geetha Kumari, D Rakesh Kumar   +3 more
doaj   +1 more source

Attitudes among dermatologists regarding non-melanoma skin cancer treatment options

Discover Oncology, 2021
Non-melanoma skin cancers include basal and squamous cell carcinoma. These tumors have become an important health issue for their high incidence and for the morbidity, especially if untreated for a long period.
Luca Fania, Tonia Samela, Gaia Moretta, Francesco Ricci, Elena Dellambra, Mara Mancini, Francesca Sampogna, Annarita Panebianco, Damiano Abeni   +8 more
doaj   +1 more source

Risk of basal cell carcinoma after Hodgkin's disease [PDF]

, 2000
Background: Basal cell cancer is a common skin cancer, yet studies of second tumors after Hodgkin's disease tend to exclude basal cell cancers as second malignant tumors from analysis.
Hölzel, Dieter, Hiller, E., Grützner, S., Munker, Reinhold, Aydemir, Ü., Schmidt, M.   +5 more
core   +1 more source

Anticoagulation Treatment Response Among Phenotypic ESUS Clusters: Evidence From CASPR

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate treatment effect heterogeneity across phenotypic clusters of patients with cryptogenic embolic stroke using causal inference methods. Methods From a retrospective, multicenter cohort of patients with cryptogenic embolic stroke, we estimated the treatment effect of anticoagulation versus antiplatelet therapy in patients ...
Elena Badillo Goicoechea, Patrick Ellsworth, James E. Siegler, James R. Brorson, Christina M. Lineback, Frank G. Conyers, Deborah Kerrigan, Kelsey Eklund, Shadi Yaghi, Farid Khasiyev, Emiliya Melkumova, Collin J. Culbertson, Marissa D'Souza, Dinesh V. Jillella, Patrick Glover, Hassan Aboul‐Nour, Fadi Nahab, Mahan Shahrivari, Simona Nedelcu, David S. Liebeskind, Matthew M. Smith, Aaron Rothstein, Anna Bowman, Alicia Zha, Narendra Kala, Ahmad Abu Qdais, Sami Al Kasab, Mudassir Farooqui, Diana Rojas‐Soto, Yasmin Aziz, Franziska Herpich, Jean‐Philippe Daniel, Sean L. Thompson, Vivek Patel, Thanh N. Nguyen, Siddharth Sehgal, Wenzheng Yu, Wayneho Kam, Russel Van Coevering, Oana M. Dumitrascu, Muhammad Alvi, Balaji Krishnaiah, Setareh Salehi Omran, Guillermo Linares, Eesha Singh, Hamid Ali, Mary Penckofer, Jesse M. Thon, Shani Mannion, Dalia Chahien, Lucia Chen, Fawad Talat, Mehdi Abbasi, Richa Sharma   +53 more
wiley   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Melanoma metastasizing into a basal cell carcinoma

, 2022
Background: Basal cell carcinomas (BCC), being the most common diagnosed skin cancer in Australia, are frequently encountered in routine practice. Rarely, these tumours occur concurrently with melanomas, given the common risk factor of UV radiation ...
Hughes, L, Gounden, S
core   +1 more source