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Locally Advanced Pancreatic Cancer: A Review of Local Ablative Therapies [PDF]

Cancers, 2018
Pancreatic cancer is typically characterized by its aggressive tumor growth and dismal prognosis. Approximately 30% of patients with pancreatic cancer present with locally advanced disease, broadly defined as having a tumor-to-artery interface >180°, having an unreconstructable portal vein or superior mesenteric vein and no signs of metastatic ...
Alette H Ruarus, Laurien G P H Vroomen, Hester J Scheffer   +2 more
exaly   +3 more sources

Management of locally advanced periampullary tumor: Multicenter study [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2021
Background: Pancreas may develop either benign or malignant tumors. Pancreatic cancer (PC) is one of the most lethal solid tumors which ranking as the fourth cause of cancer-related death in the United States. Aim:  To analyze the results of treatment of
Essam Elshikh, Taha Yassein, Eslam Ayoub, Ahmed Ebeed, Hossam Elashtokhy Hossam Elashtokhy, Walla Abdelgawad, Mohamed Elsabrout, Mosad El-lity, Tarek Youssef, Mohamed Ibrahim   +9 more
doaj   +1 more source

Geographic variation in attitudes regarding management of locally advanced pancreatic cancer

Surgery Open Science, 2022
Background: Recent literature suggests wide variations exist in the international management of locally advanced pancreatic cancer. This study sought to evaluate how geography contributes to variations in management of locally advanced pancreatic cancer.
Logan R. McNeil, BA, Alex B. Blair, MD, Robert W. Krell, MD, Chunmeng Zhang, MD, Aslam Ejaz, MD, MPH, Vincent P. Groot, MD, PhD, Georgios Gemenetzis, MD, James C. Padussis, MD, Massimo Falconi, MD, Christopher L. Wolfgang, MD, PhD, Matthew J. Weiss, MD, Chandrakanth Are, MD, MBA, Jin He, MD, PhD, Bradley N. Reames, MD, MS   +13 more
doaj   +1 more source

Radiotherapy for Locally Advanced Pancreatic Adenocarcinoma—A Critical Review of Randomised Trials

Current Oncology, 2023
Pancreatic cancer is rising as one of the leading causes of cancer-related death worldwide. Patients often present with advanced disease, limiting curative treatment options and therefore making management of the disease difficult.
Mathilde Weisz Ejlsmark, Tine Schytte, Uffe Bernchou, Rana Bahij, Britta Weber, Michael Bau Mortensen, Per Pfeiffer   +6 more
doaj   +1 more source

The evolving role of radiation in pancreatic cancer

Frontiers in Oncology, 2023
Pancreatic cancer is the fourth leading cause of cancer mortality in the United States. Chemotherapy in resectable pancreatic cancer has improved survival by 10-20%.
Midhun Malla, Fatemeh Fekrmandi, Nadia Malik, Hassan Hatoum, Sagila George, Richard M. Goldberg, Sarbajit Mukherjee   +6 more
doaj   +1 more source

Proper adjuvant therapy in patients with borderline resectable and locally advanced pancreatic cancer who had received neoadjuvant FOLFIRINOX

Frontiers in Oncology, 2022
BackgroundThe complete resection rate of pancreatic cancer has increased because of the advent of efficacious first-line treatments for unresectable pancreatic cancer.
Jin Ho Choi, Min Kyu Kim, Sang Hyub Lee, Jin Woo Park, Namyoung Park, In Rae Cho, Ji Kon Ryu, Yong-Tae Kim, Jin-Young Jang, Wooil Kwon, Hongbeom Kim, Woo Hyun Paik   +11 more
doaj   +1 more source

Stereotactic Body Radiation Therapy for Locally Advanced Pancreatic Cancer [PDF]

Clinical and Experimental Gastroenterology
Shane S Neibart,1 Shalini Moningi,1 Krishan R Jethwa2 1Department of Radiation Oncology, Brigham and Women’s Hospital/Dana-Farber Cancer Institute, Boston, MA, USA; 2Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USACorrespondence: Shalini
Neibart SS, Moningi S, Jethwa KR
doaj   +2 more sources

Staging for locally advanced pancreatic cancer [PDF]

European Journal of Surgical Oncology (EJSO), 2009
To address the role of a dedicated radiologist and high quality CT scanning in staging of patients referred with suspected locally advanced pancreatic cancer. Furthermore, the value of laparoscopy in detecting CT-occult metastases in these patients was assessed.In a prospective cohort study, 116 patients with suspected unresectable pancreatic cancer ...
Morak, Marjolein, Hermans, John, Smeenk, HG, Renders, WM, Nuyttens, J.J.M.E., Kazemier, G, van Eijck, Casper   +6 more
openaire   +4 more sources

Impact of chemoradiotherapy on the survival of unresectable locally advanced pancreatic cancer: a retrospective cohort analysis

BMC Gastroenterology, 2023
Background The role of chemoradiotherapy in unresectable locally advanced pancreatic cancer is still unclear. Methods Data from patients with unresectable locally advanced pancreatic cancer were extracted from the Surveillance, Epidemiology, and End ...
Zi-Meng Wang, Hong-Bin Ma, Yan Meng
doaj   +1 more source

Long-term survival after esophagectomy with distal pancreatectomy for locally advanced esophageal cancer with pancreatic invasion: a case report

Surgical Case Reports, 2021
Background The treatment for the locally advanced esophageal cancer invading adjacent organs is controversial. We performed a radical surgery for a patient suffering from lower esophageal cancer with pancreatic invasion, and led to long-term survival ...
Yoshiki Kaneko, Katsuji Hisakura, Koichi Ogawa, Yoshimasa Akashi, Yusuke Ohara, Yohei Owada, Tsuyoshi Enomoto, Kinji Furuya, Shoko Moue, Manami Doi, Kazuhiro Takahashi, Osamu Shimomura, Shinji Hashimoto, Noriaki Sakamoto, Tsunehiko Maruyama, Tatsuya Oda   +15 more
doaj   +1 more source