Results 11 to 20 of about 75,890 (310)

Sequential Irreversible Electroporation for Locally Advanced Pancreatic Cancer

Diagnostics, 2023
Pancreatic cancer is a lethal disease, with locally advanced pancreatic cancer (LAPC) having a dismal prognosis. For patients with LAPC, gemcitabine-based regimens, with or without radiation, have long been the standard of care.
Daniel Yuxuan Ong, Uei Pua
doaj   +3 more sources

Staging for locally advanced pancreatic cancer [PDF]

European Journal of Surgical Oncology (EJSO), 2009
To address the role of a dedicated radiologist and high quality CT scanning in staging of patients referred with suspected locally advanced pancreatic cancer. Furthermore, the value of laparoscopy in detecting CT-occult metastases in these patients was assessed.In a prospective cohort study, 116 patients with suspected unresectable pancreatic cancer ...
Morak, Marjolein, Hermans, John, Smeenk, HG, Renders, WM, Nuyttens, J.J.M.E., Kazemier, G, van Eijck, Casper   +6 more
openaire   +4 more sources

A current perspective on stereotactic body radiation therapy for pancreatic cancer. [PDF]

, 2016
Pancreatic cancer is a formidable malignancy with poor outcomes. The majority of patients are unable to undergo resection, which remains the only potentially curative treatment option.
Czito, Brian G, Hong, Julian C, Palta, Manisha, Willett, Christopher G   +3 more
core   +2 more sources

Consensus in determining the resectability of locally progressed pancreatic ductal adenocarcinoma – results of the Conko-007 multicenter trial

BMC Cancer, 2019
Background One critical step in the therapy of patients with localized pancreatic cancer is the determination of local resectability. The decision between primary surgery versus upfront local or systemic cancer therapy seems especially to differ between ...
U. A. Wittel, D. Lubgan, M. Ghadimi, O. Belyaev, W. Uhl, W. O. Bechstein, R. Grützmann, W. M. Hohenberger, A. Schmid, L. Jacobasch, R. S. Croner, A. Reinacher-Schick, U. T. Hopt, A. Pirkl, H. Oettle, R. Fietkau, H. Golcher   +16 more
doaj   +1 more source

Targeted therapies in the management of locally advanced and metastatic pancreatic cancer: a systematic review [PDF]

, 2018
Pancreatic cancer has a dismal prognosis particularly in patients presenting with unresectable tumors. We performed a bibliometric analysis of clinical trials for pancreatic cancer conducted between 2014-2016 focusing on patients that presented with ...
Biankin, Andrew V., Khachigian, Levon M., Parish, Christopher R., Sheahan, Anjali V.   +3 more
core   +1 more source

Locally Advanced Pancreatic Cancer

JOP : Journal of the pancreas, 2013
Treatment of locally advanced pancreatic cancer is palliative, based on chemotherapy and according to response, chemoradiotherapy can be applied. The authors summarize three abstracts (#LBA146, #256 and #303) presented on the 2013 ASCO Gastrointestinal Cancers Symposium, which were focused on treatment of locally advanced pancreatic cancer.
Georgios M, Oikonomopoulos, Kathryn E, Huber, Konstantinos N, Syrigos, Muhammad Wasif, Saif   +3 more
openaire   +2 more sources

Irreversible electroporation of locally advanced pancreatic cancer

Seminars in Oncology, 2021
Locally advanced pancreatic cancer (LAPC) constitutes approximately one-third of all pancreatic cancer, with standard of care inconsistently defined and achieving modest outcomes at best. While resection after downstaging offers the chance for cure, only a fraction of patients with LAPC become candidates for resection. Chemotherapy remains the mainstay
Wooil Kwon, Alexander Thomas, Michael D. Kluger   +2 more
openaire   +2 more sources

Locally Advanced Unresectable Pancreatic Cancer

JOP : Journal of the pancreas, 2014
Twenty-five percent of patients with pancreatic cancer present with locally advanced disease that is unresectable, and the treatment strategy for these patients is controversial, with options including chemotherapy alone, concurrent chemoradiation, or induction chemotherapy followed by chemoradiation. Abstracts presented at the 2014 American Society of
Kimberly L, Johung, Muhammad Wasif, Saif, Bryan W, Chang   +2 more
openaire   +2 more sources

Irreversible Electroporation for Locally Advanced Pancreatic Cancer [PDF]

Techniques in Vascular and Interventional Radiology, 2020
Several minimally invasive image guided tumor ablation techniques have been added to the treatment spectrum for locally advanced pancreatic cancer (LAPC). Irreversible electroporation (IRE) might have a significant additive value in the management of this difficult-to-treat disease.
Timmer, Florentine E.F., Geboers, Bart, Ruarus, Alette H., Schouten, Evelien A.C., Nieuwenhuizen, Sanne, Puijk, Robbert S., de Vries, Jan J.J., Meijerink, Martijn R., Scheffer, Hester J.   +8 more
openaire   +3 more sources

Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer: A Promising Approach. [PDF]

, 2018
Locally advanced pancreatic cancer (LAPC) is characterized by poor prognosis and low response durability with standard-of-care chemotherapy or chemoradiotherapy treatment.
Cao, Minsong, Lamb, James, Lee, Percy, Low, Daniel A, Luterstein, Elaine, Raldow, Ann C, Steinberg, Michael L   +6 more
core   +1 more source