Results 171 to 180 of about 39,378 (264)

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Effect of First-Line Chemotherapy Alone Versus First-Line Chemotherapy Plus Radiotherapy on Survival in Patients With Locally Advanced Pancreatic Cancer in the IMRT Era: A Retrospective Cohort Study. [PDF]

Cancer Rep (Hoboken)
Liu Z, Tian Y, Ma J, Meng DF.
europepmc   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Neoadjuvant stereotactic body vs conventionally fractionated radiation therapy for borderline resectable and locally advanced pancreatic cancer: a propensity score-matched analysis. [PDF]

J Gastrointest Surg
Shimizu T, Zheng S, Maeda S, Link J, Deranteriassian A, Premji A, King J, Girgis M, Hines OJ, Wainberg Z, Raldow A, He J, Burns W, Narang A, Qadan M, Castillo CF, Lillemoe KD, Wo J, Hong T, Donahue TR.   +19 more
europepmc   +1 more source

RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment

MedComm, Volume 7, Issue 7, July 2026.
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li, Yating Sun, Shuibin Lin, Quan Yuan   +3 more
wiley   +1 more source

Integrating surgery into multimodal treatment for locally advanced pancreatic cancer: beyond the boundaries of systemic therapy. [PDF]

Hepatobiliary Surg Nutr
Rebelo A, Kleeff J.
europepmc   +1 more source

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Radiotherapy for Locally Advanced Pancreatic Cancer in the Modern Era: A Systematic Review and Meta-Analysis. [PDF]

Cancers (Basel)
Bae SH, Jang WI, Yu JI, Park HC, Moon JE, Haustermans K, Scorsetti M, Høyer M, Kim MS.   +8 more
europepmc   +1 more source

Dynamics of Circulating Tumor DNA (ctDNA) Predict Treatment Efficacy and Prognosis in Patients With Advanced Pancreatic Cancer: A Prospective Large‐Cohort Study

MedComm, Volume 7, Issue 7, July 2026.
A total of 127 advanced pancreatic ductal adenocarcinoma (PDAC) patients receiving first‐line therapy were enrolled in this study. A series of peripheral blood collected before the initiation of treatment (B1), at the first response assessment (B2), and at subsequent timepoints to perform high‐depth next‐generation sequencing.
Tingting You, Hui Tang, Mingming Yuan, Dongfeng Song, Chenyu Wang, Jinrong Ying, Rongrong Chen, Chunmei Bai, Yuejuan Cheng, Yingyi Wang   +9 more
wiley   +1 more source

Comparison of chemoradiotherapy and gemcitabine plus nab-paclitaxel for locally advanced pancreatic cancer: an integrated analysis of two randomized phase II trials (JCOG2408A). [PDF]

BMC Cancer
Sano Y, Kajikawa R, Mizusawa J, Ioka T, Ozaka M, Nakamura S, Ito Y, Furuse J, Kobayashi S, Fukuda H, Okusaka T, Ikeda M, Miwa H, Sasahira N, Nagashima F, Ohkawa K, Yamazaki K, Kanai M, Yamashita T, Hara K, Takayama Y, Komatsu Y, Fujimori N, Hama N, Kamata K, Hisano T, Shimizu S, Tobimatsu K, Maeda S, Ueno M.   +29 more
europepmc   +1 more source