Assessment of Outcomes by Intention-to-Treat Comparison for Locally Advanced Pancreatic Cancer: A Population-Derived Cohort Study. [PDF]
Larsson P +6 more
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Study protocol: multi-centre, randomised controlled clinical trial exploring stromal targeting in locally advanced pancreatic cancer; STARPAC2. [PDF]
Kocher HM +13 more
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The impact of intensified staging and combined therapies in locally advanced pancreatic cancer: a secondary analysis of prospective studies. [PDF]
Fiore M +15 more
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Surgery for Locally Advanced Pancreatic Cancer Following Induction Chemotherapy: A Single-Center Experience. [PDF]
Theijse RT +19 more
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Locally Advanced Pancreatic Cancer
Journal of Clinical Oncology, 2005Of the 32,180 patients diagnosed with pancreatic carcinoma in the United States this year, approximately 40% will present with locally advanced disease. Radiotherapeutic approaches are often employed because these patients have unresectable tumors by virtue of local invasion into the retroperitoneal vessels in the absence of clinically detectable ...
Christopher G, Willett +3 more
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Irreversible electroporation in locally advanced pancreatic cancer
Pirogov Russian Journal of Surgery, 2023Objective. To determine the feasibility of irreversible electroporation (IRE) for locally advanced pancreatic adenocarcinoma. Material and methods. Twenty-three patients underwent IRE after chemotherapy for locally advanced pancreatic cancer between 2015 and 2022. IRE was performed during laparotomy as a rule (n=22).
A.N. Polyakov +8 more
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Therapeutic Advances in Localized Pancreatic Cancer
JAMA Surgery, 2016It is estimated that pancreatic cancer (PC) will become the second leading cause of cancer-related death in the United States by 2030.Clinical and preclinical data support the understanding that PC metastases occur early in the pathogenesis of this disease, even before the primary tumor can be detected.
Susan, Tsai, Douglas B, Evans
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Locally Advanced Pancreatic Cancer: A Review
Seminars in Oncology, 2007It is anticipated that there will be 37,170 new cases of pancreatic cancer diagnosed in the United States this year, resulting in approximately 33,370 deaths from the disease. Approximately 40% of these patients will present with locally advanced, non-metastatic disease. Treatment regimens that incorporate conventional radiation therapy for local tumor
Suzanne, Russo +3 more
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Management Options in Locally Advanced Pancreatic Cancer
Current Oncology Reports, 2014Pancreatic ductal adenocarcinoma is a highly lethal cancer that is rarely curable at the time of presentation. Unfortunately, most patients are diagnosed with either metastatic or locally advanced disease, which is not amenable to surgery owing to the high likelihood of incomplete resection.
Omar Y, Mian +3 more
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Current management of locally advanced pancreatic cancer
Nature Clinical Practice Gastroenterology & Hepatology, 2005Almost 30% of patients with pancreatic cancer present with large, locally advanced tumors in the absence of distant metastases. Because surgical resection is frequently contraindicated by vascular invasion, locally advanced pancreatic cancer has a dismal prognosis with a 6-10-month median survival.
Vivek, Maheshwari, A James, Moser
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