Results 51 to 60 of about 39,378 (264)

MULTIVISCERAL RESECTIONS IN CASES OF LOCALLY ADVANCED GASTRIC CANCER. PERIOPERATIVE RESULTS IN A HIGH-VOLUME CENTER [PDF]

Journal of IMAB
Introduction. At the time of diagnosis, gastric cancer is usually an advanced disease. This is related to poor prognosis. Despite of reported improvement of perioperative results after neoadjuvant therapy In cases of locally advanced disease without ...
Vesselin Marinov
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A case of successful conversion surgery for locally advanced pancreatic cancer with synchronous triple cancer of the lung and esophagus: a case report

Surgical Case Reports, 2022
Background The number of reports of multiple primary cancer (MPC) is increasing because of the advancement in diagnostic imaging technology. However, the treatment strategy for MPCs involving pancreatic cancer is controversial because of the extremely ...
Junya Mita, Tomohiro Iguchi, Norifumi Iseda, Kazuki Takada, Kosuke Hirose, Naoko Miura, Takuya Honboh, Yasunori Emi, Tetsuro Akashi, Seiya Kato, Noriaki Sadanaga, Hiroshi Matsuura   +11 more
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Repeated irreversible electroporation in a locally advanced pancreatic cancer

Исследования и практика в медицине, 2022
It is reasonable to consider the technical possibility and oncological feasibility of the local tumor destruction in patients with locally advanced pancreatic cancer (PCa).
A. N. Polyakov, D. V. Podluzhnyi, N. E. Kudashkin, I. S. Bazin, B. M. Medvedeva, A. Yu. Syskova, D. M. Kantieva, Yu. I. Patyutko   +7 more
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Neuron‐Derived MIF Engages VCAM1 to Fuel a Self‐Amplifying CXCL8 Loop That Drives Perineural Invasion and Metastasis in Gastric Cancer

Advanced Science, EarlyView.
Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li, Zhongya Zhai, Haiyi Yu, Renjie Qiu, Fengyu Li, Luxi Xiao, Boxi Huang, Huiying Liu, Jiayong He, Bowen Cai, Jiawen Chen, Jiang Yu, Guoxin Li, Tao Chen   +13 more
wiley   +1 more source

Evaluation of the Efficacy and Safety of FOLFOX in First-Line Treatment of Advanced Pancreatic Cancer

Journal of Oncological Sciences
Objective: In pancreatic cancer, only 15% to 20% of patients are potentially resectable at diagnosis. Current standard treatment for inoperable and metastatic patients includes: FOLFIRINOX, gemcitabine plus nab-paclitaxel, and NALIRIFOX regimens ...
Hüseyin ATACAN, Gül Sema YILDIRAN KESKİN, Gamze EMİN, Seda KAHRAMAN, Nurlan MAMMADZADE, Gizem YILDIRIM, Gökçe Gül GÜNEYSU, Berkan KARADURMUŞ, Esmanur KAPLAN TÜZÜN, Musa Barış AYKAN, İsmail ERTÜRK, Nuri KARADUMUŞ   +11 more
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Pancreatic Cancer: Multimodality treatment of locally advanced pancreatic cancer

Annals of Oncology, 1994
Summary Background The prognosis of locally advanced pancreatic cancer is poor (median survival 3–5 months). In view of the localized character of this disease several groups have explored the value of combined modality treatment. The conditions are that a good local treatment and an effective systemic treatment are available.
D.J.Th. Wagener, P.H.M. de Mulder, J.A. Wils   +2 more
openaire   +1 more source

Stromal Regulation of Tumor Perineural Invasion: A Multicellular and Neuro‐Ecological Perspective

Advanced Science, EarlyView.
This review reframes perineural invasion (PNI) as a dynamic, multicellular process within the tumor–nerve–stromal ecosystem. The authors delineate how cancer‐associated fibroblasts, Schwann cells, and immune cells remodel the neural niche to facilitate tumor spread.
Xiaoyang Lin, Yingqiao Liu, Haitao Lin, Kang Feng, Xiqiang Liu   +4 more
wiley   +1 more source

Treatment tactics for patients with borderline resectable and locally advanced pancreatic cancer

General Surgery
Objective – to evaluate the outcomes of extended pancreatic resections in the treatment of patients with borderline resectable and locally advanced pancreatic cancer and to identify strategies for improving the effectiveness of these procedures ...
V. M. Kopchak, L. O. Pererva, O. V. Duvalko, V. V. Khanenko, V. I. Trachuk, V. Y. Bondar, Z. Y. Holobor   +6 more
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Extralevator Abdominoperineal Excision Improves Overall Survival Compared to Standard Abdominoperineal Excision: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
This systematic review and meta‐analysis of 38 studies, encompassing over 5000 patients, compared extralevator abdominoperineal excision (ELAPE) with standard abdominoperineal excision (APE) in patients with advanced low rectal cancer. ELAPE was associated with significantly improved overall and disease‐free survival, reduced intraoperative perforation
Sarolta Beáta Kávási, Diana‐Elena Floria, Anett Rancz, Dániel Sándor Veres, Nándor Faluhelyi, Pál Miheller, Péter Hegyi, Szabolcs Ábrahám   +7 more
wiley   +1 more source

Efficacy and safety of gemcitabine plus erlotinib for locally advanced or metastatic pancreatic cancer: a systematic review and meta-analysis

Drug Design, Development and Therapy, 2016
Yuan Wang,1 Guo-fang Hu,1 Qian-qian Zhang,1 Ning Tang,1 Jun Guo,2 Li-yan Liu,2 Xiao Han,2 Xia Wang,2 Zhe-hai Wang2 1School of Medicine and Life Sciences, Shandong Academy of Medical Sciences, University of Jinan, 2Shandong Cancer Hospital, Shandong ...
Wang Y, Hu GF, Zhang QQ, Tang N, Guo J, Liu LY, Han X, Wang X, Wang ZH   +8 more
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