Results 61 to 70 of about 75,890 (310)

A case of pathological complete response with liposomal irinotecan + 5-FU/LV for unresectable locally advanced pancreatic cancer

Surgical Case Reports, 2022
Background Pancreatic cancer has one of the worst prognoses of any all cancers. 5-FU/leucovorin + irinotecan + oxaliplatin (FOLFIRINOX), gemcitabine (GEM) plus nab-paclitaxel regimens have been recognized as global-standard, first-line treatments for ...
Koji Kikuchi, Akira Umemura, Hiroyuki Nitta, Hirokatsu Katagiri, Masao Nishiya, Noriyuki Uesugi, Tamotsu Sugai, Keisuke Imanari, Akira Sasaki   +8 more
doaj   +1 more source

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

The role of adjuvant chemotherapy for patients with resected pancreatic cancer: Systematic review of randomized controlled trials and meta-analysis [PDF]

, 2007
Background: In patients undergoing surgery for resectable pancreatic cancer prognosis still remains poor. The role of adjuvant treatment strategies (including chemotherapy and chemoradiotherapy) following resection of pancreatic cancer remains ...
Bakkevold KE, Berger AC, Blackstock AW, Cress RD, Donna Pauler Ankerst, Gastrointestinal Tumour Study Group, Hochster HS, Kalser MH, Khanna A, Knaebel HP, Kosuge T, Luttges J, Oettle H, Ozols RF, Peto R, Regine WF, Stefan Boeck, Volker Heinemann   +17 more
core   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

The technical feasibility of an image-guided intensity-modulated radiotherapy (IG-IMRT) to perform a hypofractionated schedule in terms of toxicity and local control for patients with locally advanced or recurrent pancreatic cancer

Radiation Oncology, 2012
Background The purpose of this study was to evaluate the technical feasibility of an image-guided intensity modulated radiotherapy (IG-IMRT) using involved-field technique to perform a hypofractionated schedule for patients with locally advanced or ...
Son Seok, Song Jin, Choi Byung, Kang Young-nam, Lee Myung, Kang Ki, Jang Hong   +6 more
doaj   +1 more source

Modified Appleby Procedure with Arterial Reconstruction for Locally Advanced Pancreatic Adenocarcinoma: A Literature Review and Report of Three Unusual Cases. [PDF]

, 2016
BACKGROUND: Pancreatic body and tail ductal adenocarcinomas are often diagnosed with local vascular invasion of the celiac axis (CA) and its various branches. With such involvement, these tumors have traditionally been considered unresectable.
Lamb, Kathleen M., Latona, Jessica A., Maley, Warren R., Pucci, Michael J., Yeo, Charles J.   +4 more
core   +1 more source

Hedgehog signaling pathway and its targets for treatment in basal cell carcinoma [PDF]

, 2012
Basal cell carcinoma (BCC) of the skin is the most common type of cancer, and accounts for up to 40% of all cancers in the United States with a growing incidence rate in the last decades in all developed countries.
CUCCHI, DANILO, DE SMAELE, Enrico, GULINO, Alberto, OCCHIONE, MARIA ANNA   +3 more
core   +3 more sources

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

MULTIVISCERAL RESECTIONS IN CASES OF LOCALLY ADVANCED GASTRIC CANCER. PERIOPERATIVE RESULTS IN A HIGH-VOLUME CENTER [PDF]

Journal of IMAB
Introduction. At the time of diagnosis, gastric cancer is usually an advanced disease. This is related to poor prognosis. Despite of reported improvement of perioperative results after neoadjuvant therapy In cases of locally advanced disease without ...
Vesselin Marinov
doaj   +1 more source

A case of successful conversion surgery for locally advanced pancreatic cancer with synchronous triple cancer of the lung and esophagus: a case report

Surgical Case Reports, 2022
Background The number of reports of multiple primary cancer (MPC) is increasing because of the advancement in diagnostic imaging technology. However, the treatment strategy for MPCs involving pancreatic cancer is controversial because of the extremely ...
Junya Mita, Tomohiro Iguchi, Norifumi Iseda, Kazuki Takada, Kosuke Hirose, Naoko Miura, Takuya Honboh, Yasunori Emi, Tetsuro Akashi, Seiya Kato, Noriaki Sadanaga, Hiroshi Matsuura   +11 more
doaj   +1 more source