Results 231 to 240 of about 25,719,596 (290)

Human learning of noninvasive brain-computer interfaces via manifold geometry. [PDF]

Nat Neurosci
Busch EL, Fincke EC, Lajoie G, Krishnaswamy S, Turk-Browne NB.   +4 more
europepmc   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

Advanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan, Xinzhe Feng, Chuanju Liu, Jianfei Tong, Zhi Li, Chenxu Liu, Yutong Dong, Chen Meng, Yihong Xu, Weidong Xu   +9 more
wiley   +1 more source

Dataset on mobile video game engagement, gamer experience, and behavioral intentions among Indonesian gamers in a transient educational hub using PLS-SEM. [PDF]

Data Brief
Chelindiva F, Megawati V, Laurence.
europepmc   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

How large language models judge and influence human cooperation. [PDF]

PNAS Nexus
Pires AS, Samson L, Ghebreab S, Santos FP.   +3 more
europepmc   +1 more source

The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design. [PDF]

JMIR Res Protoc
Smoktunowicz E, Maciejewski J, Lesnierowska M, Pietrzak M, Großwendt F, Mayer G, Schultz JH, Tschobur N, McKendrick M, Stocks H, Floris F, Guglielmi D, Haddi Z, Mazzola C, Mlakar I, Smrke U, Fernández García L, Parra Vidales E, Sáez Muñoz E, Bruchhaus S, Hemmje M, Heutelbeck D, Diarra D, Nasser H, Butean A, Polak M, Mourettou P, Parmatzias A, Kolinska U, Schwannauer M.   +29 more
europepmc   +1 more source

Return to Sport After Foot and Ankle Surgery Is Inconsistently Defined and Assessed: A Systematic Review. [PDF]

Arthrosc Sports Med Rehabil
Oikonomou K, Savsani K, Wyatt P, Cyrus J, Ernst B, Anastasio AT, O'Neill CN, Goodloe JB, Amendola A.   +8 more
europepmc   +1 more source

Effects of motor-cognitive dual-task training on executive function in older adults with mild cognitive impairment: A multilevel dose-response meta-analysis. [PDF]

J Exerc Sci Fit
Yin X, Qin Z, Dai S, Zhong X, Zhang X, Wang Y, Qiu P, Jiang C.   +7 more
europepmc   +1 more source