Results 231 to 240 of about 25,719,596 (290)

Human learning of noninvasive brain-computer interfaces via manifold geometry. [PDF]

open access: yesNat Neurosci
Busch EL   +4 more
europepmc   +1 more source

Digoxin Alleviates Osteoarthritis by Inhibiting Macrophage Extracellular Trap Formation via Disruption of the LSP1‐SOD1 Interaction

open access: yesAdvanced Science, EarlyView.
Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan   +9 more
wiley   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

How large language models judge and influence human cooperation. [PDF]

open access: yesPNAS Nexus
Pires AS   +3 more
europepmc   +1 more source

The Preliminary Efficacy and Feasibility of SMILE Serious Game for Adolescents and Young Adults: Protocol for Cluster Randomized Multisite Adaptive Trial Design. [PDF]

open access: yesJMIR Res Protoc
Smoktunowicz E   +29 more
europepmc   +1 more source

Return to Sport After Foot and Ankle Surgery Is Inconsistently Defined and Assessed: A Systematic Review. [PDF]

open access: yesArthrosc Sports Med Rehabil
Oikonomou K   +8 more
europepmc   +1 more source

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