Results 61 to 70 of about 47,919 (264)

Campus Changer: A Serious Geogame for Transforming the Main Campus of the Warsaw University of Technology

Urban Planning
The goal of the article was to develop a serious geogame that allows for the activation of the Warsaw University of Technology’s (WUT) academic community’s involvement in the participatory planning process for campus revitalization and development.
Agnieszka Wendland, Kornel Samociuk, Anna Szalwa, Iker Bengoetxea Arruti, Urszula Szczepankowska-Bednarek, Jacek Wesołowski, Joanna Wnuk, Robert Olszewski   +7 more
doaj   +1 more source

3D Space-Time Visualization of Player Behaviour in Pervasive Location-Based Games

International Journal of Computer Games Technology, 2008
Location-based games not only offer new experiences for the players, but also present new challenges for researchers in terms of analyzing player behaviour.
Paul Coulton, Will Bamford, Keith Cheverst, Omer Rashid   +3 more
doaj   +1 more source

Behavioural Effects of Spatially Structured Scoring Systems in Location-Based Serious Games—A Case Study in the Context of OpenStreetMap

ISPRS International Journal of Geo-Information, 2020
Location-based games have become popular in recent years, with Pokémon Go and Ingress being two very prominent examples. Some location-based games, known as Serious Games, go beyond entertainment and serve additional purposes such as data collection.
Rene Westerholt, Heinrich Lorei, Bernhard Höfle   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Scavenger Hunt: Utilization of Blockchain and IoT for a Location-Based Game

IEEE Access, 2020
Distributed Ledger Technology, has been gaining enormous attention in areas beyond cryptocurrency. Industries such as energy, transportation, and healthcare are already integrating DLTs into their operations.
Ahsan Manzoor, Max Samarin, David Mason, Mika Ylianttila   +3 more
doaj   +1 more source

Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley   +1 more source

Location Privacy Protection Systems in Presence of Service Quality and Energy Constraints

Information, 2019
The wide-ranging application of location-based services (LBSs) through the use of mobile devices and wireless networks has brought about many critical privacy challenges.
Mulugeta Kassaw Tefera, Xiaolong Yang
doaj   +1 more source

The Hybrid Space of Collaborative Location-Based Mobile Games and the City: A Case Study of Ingress

Urban Planning, 2020
Structural changes in the way we live and interact in cities are occurring due to advances in mobile communication technologies affecting everyday practices.
Ulysses Sengupta, Mahmud Tantoush, May Bassanino, Eric Cheung   +3 more
doaj   +1 more source