Results 51 to 60 of about 195,956 (312)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
BeaconPass: A Location Based APP Game for Traveler [PDF]
, 2015 BeaconPass is a smartphone/tablet application inspired by shared problems among travelers. Following our previews research; lack of internet access, GPS inaccuracy, battery life and insufficient site-specific information, reflect on travelers getting lost and missing on their touring expectations.
Tsung-Yuan Ho +5 more
openaire +1 more source
Agent-Based Evolutionary Game Dynamics [PDF]
Producción CientíficaThis book is a guide to implement and analyze simple agent-based evolutionary models using NetLogo. All the models we implement in this book are agent-based, i.e.
Izquierdo Millán, Luis R. +4 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Influence of Virtual Reality on High School Students' Conceptions of Cells [PDF]
Journal of Universal Computer Science, 2020 Cells are central to the study of biology, yet many learners have difficulties understanding the abstract yet fundamental foundation of life. Research suggests that students' conceptions of cells are reinforced by current biology learning materials ...
Meredith Thompson +7 more
doaj +3 more sources
Will in Town, ein Location-based Game
, 2014 {"references": ["https://github.com/DHd-Verband/DHd-Abstracts-2014"]}
Gerrit Weber +2 more
openaire +2 more sources
Picking pockets on the lawn: the development of tactics and strategies in a mobile game [PDF]
, 2005 This paper presents Treasure, an outdoor mobile multiplayer game inspired by Weiser’s notion of seams, gaps and breaks in different media. Playing Treasure involves movement in and out of a wi-fi network, using PDAs to pick up virtual ’coins’ that may be
Tennent, P. +13 more
core +1 more source
, 2021 Driven by the growing popularity of serious games and their great potential for teaching and learning, the use of game-based learning (GBL) is gaining importance in and out of schools and is linked to high expectations in terms of motivation and learning
Michael Jüttler +5 more
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Discovering the invisible city: Location-based games for learning in smart cities [PDF]
Interaction Design and Architecture(s), 2013 In this paper we discuss how location-based mobile games can be designed for learning in modern technology enhanced public spaces. We start with the description of the design process and we identify the main challenges faced. We elaborate the case of the
Christos Sintoris +3 more
doaj