Results 31 to 40 of about 7,596,422 (242)

Modified Differential Evolution Algorithm Solving the Special Case of Location Routing Problem

open access: yesMathematical and Computational Applications, 2018
This research article aims to solve the special case of the location routing problem (SLRP) when the objective function is the fuel consumption. The fuel consumption depends on the distance of travel and the condition of the road.
Raknoi Akararungruangkul   +1 more
doaj   +1 more source

A Nonlinear Integer Programming Model for Integrated Location, Inventory, and Routing Decisions in a Closed-Loop Supply Chain

open access: yesComplexity, 2018
Facility location, inventory management, and vehicle routing are three important decisions in supply chain management, and location-inventory-routing problems consider them jointly to improve the performance and efficiency of today’s supply chain ...
Hao Guo   +4 more
doaj   +1 more source

A Multi-Objective Optimization Model For Location-Inventory-Routing Problem in a Multi-Echelon Supply Chain Network Considering Maximum Demand Coverage [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2019
Today, intense competition in global markets has forced companies to design and manage of supply chains in a better way. Since the role of three factors: location, routing and inventory is important to continue the life of a supply chain so, integration ...
Behnam Vahdani   +1 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Efficiently solving open capacitated location-routing problems through a discrete fireworks algorithm

open access: yesFrontiers in Industrial Engineering
In the open capacitated location-routing problem (OCLRP), a fleet of distribution vehicles departs from selected depots to satisfy customers’ demands, but they do not need to return to their starting depots after serving all customers.
Huizhen Zhang   +2 more
doaj   +1 more source

An improved genetic algorithm for optimizing total supply chain cost in inventory location routing problem

open access: yesAin Shams Engineering Journal, 2019
Integrating inventory, location, and routing decisions in supply chains may considerably impact their performance. In this paper, the Inventory Location Routing Problem (ILRP) is considered while adopting the Vendor Managed Inventory (VMI) strategy.
Ahmad Sayed Saif-Eddine   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Combining Heuristics with Simulation and Fuzzy Logic to Solve a Flexible-Size Location Routing Problem under Uncertainty

open access: yesAlgorithms, 2021
The location routing problem integrates both a facility location and a vehicle routing problem. Each of these problems are NP-hard in nature, which justifies the use of heuristic-based algorithms when dealing with large-scale instances that need to be ...
Rafael D. Tordecilla   +5 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

HOW HALAL TRANSPORTATION SYSTEM IMPACT THE LOCATION ROUTING PROBLEM

open access: yesJournal of Engineering and Management in Industrial System, 2017
Halal products become more popular in the world market today that increase the demand of other halal services especially in halal distribution system. These services are designed not only for profitability but its ability to serve customers to maintain ...
Oki Anita Candra Dewi, Luki Trihardani
doaj   +1 more source

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