Results 111 to 120 of about 37,587 (298)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Locative media in children´s digital books: designing new narratives on space
Texto DigitalThis paper investigates how locative media strategies in children's books can promote spatial knowledge. Locative media relates information to space, which is considered one of the central elements of the narrative.
Cristina Colombo Nunes +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
idea journal, 2020 Smartphones and social media create locative atmospheres: transportable, affective spaces modulated by the data of our temporal, networked identities. How might these atmospheres form, and how can we consider them in interior design? The conditions of these locative atmospheres are emergent; our practices with technology evolve quickly, requiring an ...
openaire +1 more source
Where has the new information gone? : the chinese case [PDF]
, 2013 In this paper I would like to show that the principles which have been proposed so far to account for the relationship between the informational level and the syntactic level in a Chinese utterance are unable to predict some interesting and regular facts
Paris, Marie-Claude
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Both symbolic and embodied representations contribute to spatial language processing: Evidence from younger and older adults [PDF]
, 2015 Building on earlier neuropsychological work, we adopted a novel individual differences approach to examine the relationship between spatial language and a wide range of both verbal and nonverbal abilities.
Coventry, Kenny +3 more
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Parallel grammaticalizations in Tibeto-Burman : evidence of Sapir's 'Drift' [PDF]
, 2010 In chapters seven and eight of his book Language, Sapir talked about what he called ‘drift’, the changes that a language undergoes through time [...]. Dialects of a language are formed when that language is broken into different segments that no longer ...
LaPolla, Randy J.
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source