Results 121 to 130 of about 7,497 (294)

The construction of locative situations: locative media and the Situationist International, recuperation or redux?

open access: yes, 2009
A trend exists within locative media art of invoking the practices of the Situationist International (SI) as an art historical and theoretical background to contemporary practices.
McGarrigle, Conor, Conor McGarrigle
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

The locative preposition in XiTsonga [PDF]

open access: yes, 2019
Thesis (M. A. (Translation Studies and Linguistics)) -- University of Limpopo, 2019The aim of this study is to find out whether or not there are locative prepositions in Xitsonga. If so, to determine if they are true prepositions, their functions and the
Masonto, Rivalani Xenon
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Three kinds of locative preposing

open access: yes, 2016
Culicover and Levine (2001) distinguish two kinds of locative inversion in English based on their divergent behaviour in a number of syntactic tests: heavy inversion and light inversion.
Bruno, Chris
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Semantic structures of English locative prepositional phrases

open access: yes, 1996
A locative prepositional phrase is decomposed into three semantic elements: locative relation, reference entity and place value. Some prepositions are unspecified with place value meaning, thus they are able to co-occur with another preposition which has
Zhang, Ning
core  

Privacy at the Margins| Being at Home with Privacy: Privacy and Mundane Intimacy Through Same-Sex Locative Media Practices

open access: yesInternational Journal of Communication, 2018
Smartphones have ushered in new forms of locative media through the overlay of global positioning system digital media onto physical places. Whereas mobile communication research has focused on corporate, hierarchical, or government surveillance ...
Larissa Hjorth   +2 more
doaj  

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