Results 61 to 70 of about 22,242 (303)

Argument structure and agency in Bemba passives [PDF]

open access: yes, 2010
Bemba employs two passive constructions: an older one with verbal extension -w- and a more recent construction involving the class 2 subject marker ba-. We argue that ba- is ambiguous between an ordinary, referential class 2 marker, and an underspecified
Kula, Nancy, Marten, Lutz
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

La diathèse circonstancielle et la coprédication : l’exemple de la structure N0 voit Inf N1 / N1 Inf (N2)

open access: yesCorela, 2020
The French construction N0 voit Inf N1 / N1 Inf (N2) introduces what we call a “circumstantial diathesis” which is related to the passive diathesis insofar as it promotes a locative (spatial or temporal) adjunct to the grammatical subject function by ...
Raja Gmir
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The syntax of existential sentences in Serbian [PDF]

open access: yes, 2008
Freeze (1992) argued on the basis of data from several different languages that there is a close relationship between existential sentences (stating the existence of an entity) and locative sentences (stating the location of an entity).
Hartmann, Jutta M., Milicevic, Nataša
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Construcciones pasivas con estar

open access: yesEstudios de Lingüística, 2004
In this paper, we will intend to demonstrate that some constructions consisting of estar and a past participle are stative passives in between a periphrastic voice construction and an attributive sentence.
Carmen Conti Jiménez
doaj   +1 more source

External versus internal possessor structures and inalienability in Russian [PDF]

open access: yes, 2003
This study deals with the choice between two external possessor structures in Russian: the possessive dative and the U + genitive PP. Is shows that this choice is primarily related to the thematic role of the possessor adjunct, which can vary with the ...
Paykin, Katia, Van Peteghem, Marleen
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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