Results 81 to 90 of about 1,436 (295)
Many languages have specialized locative words or morphemes translating roughly into words like ‘front,’ ‘back,’ ‘top,’ ‘bottom,’ ‘side,’ and so on.
Peter Svenonius
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Locative inversion and optional features
Published as a special volume of the Coyote Papers: The University of Arizona Working Papers in Linguistics.Some locative PPs in English can be optionally fronted in a certain environment, as the following examples show: 1 ( 1) a.
Kim, Jeong-Seok
core
Analyse sémantique des constructions locatives statiques en koyaga, langue mandé de Côte d’Ivoire [PDF]
Résumé :Cette étude analyse non seulement les items verbaux, mais aussi les marqueurs lexicaux de localisation employés par les locuteurs koyaga dans leurs constructions locatives pour exprimer les relations spatiales statiques.
Fréjuss Yafessou KOUAME & Yassine Juliette KAMAGATE
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Comparison in Kambaata: Superiority, Equality and Similarity
This paper is an in-depth study of the expression of comparison in Kambaata, a Highland East Cushitic language of Ethiopia. It discusses not only quantitative comparison, i.e. comparison of relative and absolute inequality and comparison of equality, but
Yvonne Treis
doaj +1 more source
PERILAKU DAN MAKNA VERBA DALAM BAHASA MADURA
This study is aiming at studying the category and the meaning of verb in Madura language. The problem to study is how to know: firm or morphological category, syntactic category, and meaning of verbs in Madura language in enjd'-iyd.
Akhmad Sofyan
doaj +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source

