Results 71 to 80 of about 614 (261)

PERILAKU DAN MAKNA VERBA DALAM BAHASA MADURA

open access: yesHumaniora, 2012
This study is aiming at studying the category and the meaning of verb in Madura language. The problem to study is how to know: firm or morphological category, syntactic category, and meaning of verbs in Madura language in enjd'-iyd.
Akhmad Sofyan
doaj   +1 more source

The Construction of Locative Situations: the Production of Agency in Locative Media Art Practice

open access: yes, 2012
This thesis is a practice led enquiry into Locative Media (LM) which argues that this emergent art practice has played an influential role in the shaping of locative technologies in their progression from new to everyday technologies. The research traces LM to its origins at the Karosta workshops, reviews the stated objectives of early practitioners ...
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Causatives with small clause complements

open access: yesIsogloss
We discuss the syntactic properties of a small subset of verbs in European Portuguese (EP) that have a causative interpretation and may also have a locative meaning, namely pôr a ‘put to / make’ and deixar a ‘make’.
Anabela Gonçalves, Ana Lúcia Santos
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Locationals: Existential, locative, and possessive constructions

open access: yes, 1978
This paper is a classic typological study of existential clauses, predlocative clauses, and predpossessive clauses, which are often coded similarly in the world's languages. Clark, Eve V. 1978. Locationals: Existential, locative, and possessive constructions. In Greenberg, Joseph H. (ed.), Universals of human language, Vol. 4: Syntax, 85–126. Stanford:
openaire   +2 more sources

The Psycho-Grammatical Description of the Existential Locative “there” Constructions [PDF]

open access: yesArmenian Folia Anglistika, 2009
The article discusses problems related to the psycho-grammatical description of the existential locative “there” constructions.The research indicates that the psycho-grammatical processes not visible to the naked eye in a sentence at first glance, may have their specific expressions in discourse.
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Lexical-constructional integration in non-prototypical English middles: the role of high-level metonymy as a motivating factor

open access: yesJournal of English Studies, 2013
The main aim of this paper is to consider the issue of lexicalconstructional integration in circumstantial English middles with instrumental and locative subjects, exemplified respectively by Narrow tyres manoeuvre more easily and The tennis court plays ...
Pilar Guerrero Medina
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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