Results 71 to 80 of about 22,242 (303)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Transfer, 2017 Prepositional phrases are the commonest kind of postmodification in all registers of English (Biber et al. 1999: 634). The locative ones that can be expanded into a defining relative clause (the books [which are] on the table) are usually expressed by ...
Brian Mott
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Direct and indirect speech in Tagalog [PDF]
, 2010 Tagalog is an Austronesian language of the Philippines. It is the basis for one of the two official languages of the Philippines, Pilipino, and as such potentially spoken by 81 million people, though there are many sub ...
LaPolla, Randy J., Poa, Dory
core
A usage based approach into the acquisition of relative clauses [PDF]
, 2016 : Previous research has shown that cross-linguistically relative clauses are acquired late and are considered as a signal of linguistic complexity. This study adapts a usage-based account of relative clause acquisition in Turkish. A corpus based on three
Altan, Aslı, Altinkamis, Feyza
core +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Constituent structure of a Tagalog text [PDF]
, 2010 This paper is an inductive look at the constituents found in a randomly selected Tagalog text, Bob Ong’s Alamat ng Gubat (Makati City, MM: Visual Print Enterprises, 2004). The analysis is based on the full text, but we will only be able to go through the
LaPolla, Randy J.
core
Derived subjects in Kinyarwanda locative constructions
Stellenbosch Papers in Linguistics Plus, 2012 No Abstract.
openaire +4 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source