Results 91 to 100 of about 12,931 (333)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

VARIABILITY OF MULTIPLE INTERPRETATIONS OF LOCATIVE-TEMPORAL CHARACTERISTICS OF A MEDIA EVENT

open access: yesВестник Кемеровского государственного университета, 2015
The article describes one of the factors influencing the interpretation of events in the media. The process of verbalization creates a cognitive model of the event, which is projected in a variety of media texts on the lexical and grammatical level ...
S. V. Mokhireva
doaj  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Alternate Reality Game and Culural Heritage: The “Aequilibrium” Project

open access: yesDigital Studies, 2015
"Aequilibrium" is a transmedia and location-based experience which engages players in an adventure that blurs the boundaries between digital and physical spaces, imaginary and real people from the local community.
Domenico Morreale, Giulia Bertone
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Role of Hackers in Countering Surveillance and Promoting Democracy

open access: yesMedia and Communication, 2015
Practices related to media technologies and infrastructures (MTI) are an increasingly important part of democratic constellations in general and of surveillance tactics in particular. This article does not seek to discuss surveillance per se, but instead
Sebastian Kubitschko
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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