Results 71 to 80 of about 12,931 (333)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Socio-spatial visualisations of cultural routes
Netcom, 2018 Cultural routes, defined as routes of historical importance that geographically represent the shared and living cultural heritage of different countries, have recently gained attention both as tourist destinations and as social repositories of collective
Catherine Emma (Kate) Jones +2 more
doaj +1 more source
An Infrastructural Approach to Digital Ethnography: Lessons from the Manchester Infrastructures of Social Change Project [PDF]
, 2016 With the increase of digital and networked media in everyday life, researchers have increasingly turned their gaze to the symbolic and cultural elements of technologies.
Knox, HC
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Ocula, 2017 Reggiane Urban Gallery is a virtual museum based on the abandoned industrial plant of ex-Officine Reggiane in Reggio Emilia, now in restoration. Along the years the place has become an open space for local and national street-artists.
Damiano Razzoli
doaj +1 more source
The uneven price impact of energy efficiency ratings on housing segments and implications for public policy and private markets [PDF]
, 2019 In the literature, there is extensive, although in some cases inconclusive, evidence on the impact of Energy Performance Certificates (EPC) on housing prices.
Chen, Ai +1 more
core +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Reflect – renew – refresh [PDF]
, 2018 No abstract ...
Lorimer, Hayden, Winders, Jamie
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Digital Studies, 2017 Humanities scholars have long claimed the importance of browsing in the library stacks as part of their research process. The digitization practices of libraries and archives, while meant to assist with preservation and access, make the physical browsing
Anabel Quan-Haase +2 more
doaj +1 more source