Results 51 to 60 of about 144,627 (328)
Study on Optimization of Copper to Aluminum for Locomotive Finned Tube Radiator
Energies, 2023 The influence of the improvement of the finned tube radiator unit structure on the fluid flow and heat transfer effect of the locomotive was studied. A saw-toothed fin structure with aluminum instead of copper was proposed to keep the position and size ...
Ying Guan, Hongjiang Cui, Jiyou Fei
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Development of Urban Electric Bus Drivetrain [PDF]
, 2019 The development of the drivetrain for a new series of urban electric buses is presented in the paper. The traction and design properties of several drive variants are compared.
Chyský J. +5 more
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu［Objective］In order to ensure train operation safety and passenger comfort, it is necessary to study the chang-ing laws of aerodynamic force and pressure inside the city railway train when passing through the variable cross-section positions in the ...
ZHANG Baozhen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu[Objective] The architecture of traditional urban rail transit train control system faces challenges such as complex train network topology and wiring, increased delays in subsystem interactions, and poor coordination in complex control processes.
YANG Weijun +5 more
doaj +1 more source
Energies, 2023 EMU (electric multiple unit) traction motors are powered by converters whose output voltage increases the voltage stress borne by the insulation system, making the ITSC (inter-turn short-circuit) fault more prominent.
Jie Ma +5 more
doaj +1 more source