Results 71 to 80 of about 1,574,453 (263)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

conting: An R Package for Bayesian Analysis of Complete and Incomplete Contingency Tables

open access: yesJournal of Statistical Software, 2014
The aim of this paper is to demonstrate the R package conting for the Bayesian analysis of complete and incomplete contingency tables using hierarchical log-linear models. This package allows a user to identify interactions between categorical factors (
Antony M. Overstall, Ruth King
doaj   +1 more source

A COMPLETE CHARACTERIZATION OF THE LINEAR, LOG-LINEAR, AND SEMI-LOG INCOMPLETE DEMAND SYSTEM MODELS [PDF]

open access: yes
This study extends LaFranceÂ’'s (1985, 1986, 1990) previous research by deriving the necessary parameter restrictions for two additional classes of incomplete demand system models to be integrable.
von Haefen, Roger H.
core   +1 more source

A Framework to Interpret Nonstandard Log-Linear Models [PDF]

open access: yes, 2007
The formulation of log-linear models within the framework of Generalized Linear Models offers new possibilities in modeling categorical data.
Mair, Patrick
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Semiparametric estimation for a class of time-inhomogenous diffusion processes [PDF]

open access: yes, 2009
Copyright @ 2009 Institute of Statistical Science, Academia SinicaWe develop two likelihood-based approaches to semiparametrically estimate a class of time-inhomogeneous diffusion processes: log penalized splines (P-splines) and the local log-linear ...
Li, M, Wang, H, Yu, K, Yu, Y
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

PENENTUAN BENTUK FUNGSI MODEL EMPIRIK: STUDI KASUS PERMINTAAN KENDARAAN RODA EMPAT BARU

open access: yesJEJAK: Jurnal Ekonomi dan Kebijakan, 2012
In many cases, the determination of form of the regression function of the empirical model betweenthe linear model and the log-linear model is neglected when someone starts research.
Andryan Setyadharma
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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