Results 221 to 230 of about 387,211 (278)

Long-term effects of systemic ceftiofur and ampicillin on the abundance and duration of shedding of resistant Gram-negative bacteria in the feces of healthy dairy cows: a randomized clinical trial. [PDF]

Front Vet Sci
Gonçalves JL, Silva ATF, Vasco K, Robison CI, Manning SD, Zhang L, Norby B, Mani R, Ruegg PL.   +8 more
europepmc   +1 more source

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 966-978, October 2026.
This study investigated genetic determinants of the pharmacokinetics of the CYP2C8 index drugs repaglinide and gemfibrozil, and their interaction in healthy participants. Sequencing data from a study with montelukast revealed a novel functional CYP2C8 allele (rs2071426, CYP2C8*19), predicted to create an intronic splice donor site.
Anssi J. H. Mykkänen, Päivi Hirvensalo, Kathrin Klein, Dorota Kaminska, Markus Grube, Tuija Tapaninen, Johanna I. Kiiski, Mikko Neuvonen, Ville T. Männistö, Jussi Pihlajamäki, Mladen Tzvetkov, Matthias Schwab, Aleksi Tornio, Janne T. Backman, Mikko Niemi   +14 more
wiley   +1 more source

Dung Beetle with Reflection Cuckoo Catfish Optimizer for Numerical Optimization and Reservoir Production Optimization. [PDF]

Biomimetics (Basel)
Li S, Yin T.
europepmc   +1 more source

Analytical Framework for System‐Level Fragility Surfaces of Reinforced Concrete Bridges Under Mainshock‐Aftershock Sequences

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 13, Page 3264-3284, 25 October 2026.
ABSTRACT Conventional single intensity measure (IM) fragility approaches with simplified component dependency assumptions overlook the progressive damage accumulation and evolving inter‐component correlations that govern system behavior under mainshock‐aftershock (MSAS) loading.
Muhammad Rashid, Mayuko Nishio
wiley   +1 more source

Cable online partial discharge detection and state evaluation based on deep belief network and swarm intelligence optimization algorithm. [PDF]

Sci Rep
Hou Y, Li Y, Song B, Gong C, Yang M, Yao L, Shi D.   +6 more
europepmc   +1 more source

Surrogate‐Based Time‐Continuous Seismic Fragility Assessment of Corrosion‐Deteriorated Reinforced Concrete Bridges Under Climate Change

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 13, Page 3338-3362, 25 October 2026.
ABSTRACT Seismic fragility assessment of reinforced concrete (RC) bridges exposed to corrosive environments must reliably capture time‐dependent deterioration impacts. Climate change compounds this challenge through nonstationary temperature and humidity variations that accelerate bridge corrosion.
Yexiang Yan, Yazhou Xie
wiley   +1 more source

SOPAR: Bee Localization and Tracking Using RF Sub-harmonic Oscillating Parametric Resonator in Hive Environments. [PDF]

Proc ACM Interact Mob Wearable Ubiquitous Technol
Wang Q, Yan P, Zhou GJ, Liu X, Stanley D, Huang Z, Qian C, Zeng H.   +7 more
europepmc   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, Volume 159, Issue 7, Page 1715-1734, 1 October 2026.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Spiral defect chaos with intermittency increases mean termination time. [PDF]

Phys Rev E
Mulimani MK, Rappel WJ.
europepmc   +1 more source

From Resource Activation to Utilization: A Process‐Outcome Analysis in Telephone‐Based Cognitive‐Behavioral Therapy for Family Caregivers of People With Dementia

Journal of Clinical Psychology, Volume 82, Issue 10, Page 1540-1552, October 2026.
ABSTRACT Objective This study aimed to assess whether resource activation (i.e., fostering strengths and healthy aspects of the patient), aggregated across therapy sessions during telephone‐based cognitive‐behavioral therapy (TEL‐CBT), is associated with post‐therapy psychosocial resource utilization (i.e., the extent to which individuals utilize ...
Nils F. Töpfer, Robin Wester, Gabriele Wilz   +2 more
wiley   +1 more source