Results 61 to 70 of about 387,211 (278)

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

open access: yesAdvanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi   +3 more
wiley   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

open access: yesAdvanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li   +8 more
wiley   +1 more source

Monotonicity and Inequalities for Ratio of the Generalized Logarithmic Means [PDF]

open access: yes, 2003
Let c > b > a > 0 be real numbers. Then the function f(r) = Lr(a,b)/Lr(a,c) is strictly decreasing on (−∞,∞), where Lr(a, b) denotes the generalized (extended) logarithmic mean of two positive numbers a and ...
Qi, Feng, Chen, Chao-Ping
core   +5 more sources

The Research of the Logarithmic Spiral Axis and NC Machining

open access: yes, 2010
The characteristics of surface connection include high fatigue strength, high centering ability, easy dismantling and long life. According to these characteristics and based on the analysis of logarithmic spiral equation, the article explores a new ...
Ning Luo   +3 more
core   +1 more source

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus

open access: yesAdvanced Science, EarlyView.
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Matteo Tollemeto   +5 more
wiley   +1 more source

基于折算齿形法的非封闭型非圆齿轮齿廓绘制

open access: yesJixie chuandong, 2014
The enclosed pitch curve of logarithmic spiral of non-circular gear tooth profile is generated in CAXA via the gear meshing theory and the conversion method of tooth profile for the enclosed pitch curve of non-circular gear tooth profile generation ...
王鹏, 刘永平, 何贵平
doaj  

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang   +6 more
wiley   +1 more source

From Flow to Function: Using Different Static Mixers to Fabricate Microarchitected Materials Via Chaotic Printing

open access: yesAdvanced Science, EarlyView.
Complex microarchitectures emerge from simple flow‐driven transformations as static mixers iteratively reorient and split material domains. Coupled with diverse deposition strategies, chaotic printing provides an accessible platform for fabricating architected materials that support biologically and chemically relevant processes. ABSTRACT Nature builds
Edna Johana Bolívar‐Monsalve   +7 more
wiley   +1 more source

Improved Ant Lion Optimizer Based on Spiral Complex Path Searching Patterns

open access: yesIEEE Access, 2020
Ant Lion Optimizer (ALO) is a new meta-heuristic algorithm that simulates the ant lion predator mechanism in nature. Five main steps of hunting include: random walks of ants, building traps, trapping in antlion's pits, sliding ants towards antlion ...
M. W. Guo   +4 more
doaj   +1 more source

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