Results 41 to 50 of about 3,137 (197)

Scanning Electron Microscopy Observations of Loa loa (Nematoda)

Case Reports in Ophthalmology, 2020
We present a case report of periocular Loa loa. The key feature of L. loa distinguishing it from other human filarial parasites are cuticular bosses, which are presented in images from a light microscope and a scanning electron microscope.
Jens Anibal Juul, Vegard Asgeir Forsaa, Tor Paaske Utheim, Endre Willassen   +3 more
doaj   +1 more source

Excess Mortality Associated With Loiasis: Confirmation by a New Retrospective Cohort Study Conducted in the Republic of Congo

Open Forum Infectious Diseases, 2023
Background Loiasis (Loa loa filariasis) is considered a benign disease and is currently not included in the World Health Organization’s (WHO's) list of Neglected Tropical Diseases, despite mounting evidence suggesting significant disease burden in ...
Marlhand C. Hemilembolo, A. Niama, Jérémy T. Campillo, S. Pion, François Missamou, C. Whittaker, J. Kankou, Gilbert Ndziessi, R. Bileckot, M. Boussinesq, C. Chesnais   +10 more
semanticscholar   +1 more source

The therapeutic efficacy and macrofilaricidal activity of doxycycline for the treatment of river blindness [PDF]

, 2014
Background. Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival.
Achim Hoerauf, Agwuh, Basáñez, Basáñez, Bosshardt, Cattamanchi, Chib, Churcher, de Andrade, Debrah, Duke, Duke, Gardon, Gelman, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Hoerauf, Mand, Mark J. Taylor, Martin Walker, María-Gloria Basáñez, Norton, Osei-Atweneboana, Plaisier, Plaisier, Roberts, Sabine Specht, Specht, Tamarozzi, Taylor, Taylor, Taylor, Taylor, Taylor, Thomas S. Churcher, van Rie, Wanji, Wearing, World Health Organization, Xia   +43 more
core   +2 more sources

Loa loa Infection in Pregnant Women, Gabon [PDF]

, 2015
Loa loa, the African eye worm, is a filarial pathogen of Central African rainforest regions. As of 2013, it had affected an estimated 2–3 million persons in Central Africa (1,2).
Adegnika, Ayôla A., Basra, Arti, González, Raquel, Kremsner, Peter G., Lotsch, Felix, Mabika, Barthelemy, Mackanga, Jean Rodolphe, Manego, Rella Zoleko, Matsiegui, Pierre-Blaise, Menéndez, Clara, Mesküre Capan-Melse, Mombo-Ngoma, Ghyslain, Ramharter, Michael, Yazdanbakhsh, Maria   +13 more
core   +1 more source

Microorganisms and Common Ophthalmic Diseases [PDF]

, 2017
The human eye is in constant contact to environmental conditions that increase its likelihood in being exposed to a multitude of pathogens. Studies have revealed that the normal microbial flora found around the ocular area contribute to the well-being of
Su CW, Tighe S
core   +1 more source

Innovative tools for assessing risks for severe adverse events in areas of overlapping Loa loa and other filarial distributions: the application of micro-stratification mapping

Parasites & Vectors, 2014
Background The wide distribution of Loa loa infection (loiasis) throughout the Democratic Republic of Congo (DRC) is a major obstacle to the plans to eliminate onchocerciasis and lymphatic filariasis (LF) because the standard drug regime is dependent on ...
Louise A Kelly-Hope, Jorge Cano, Michelle C Stanton, Moses J Bockarie, David H Molyneux   +4 more
doaj   +1 more source

Efficacy, safety, and tolerability of albendazole and ivermectin based regimens for the treatment of microfilaraemic loiasis in adult patients in Gabon: A randomized controlled assessor blinded clinical trial

PLoS Neglected Tropical Diseases, 2023
Background There is a lack of systematic evidence for strategies to control loiasis transmission in highly endemic regions. Here we assessed albendazole and ivermectin based treatment regimens to reduce Loa loa microfilaraemia in Gabon.
Rella Zoleko-Manego, Ruth Kreuzmair, L. Veletzky, Wilfrid F Ndzebe-Ndoumba, Dorothea Ekoka Mbassi, D. G. Okwu, Lia B. Dimessa-Mbadinga-Weyat, Roselyne D. Houtsa-Temgoua, Johannes Mischlinger, M. McCall, Peter G. Kresmner, S. Agnandji, Betrand Lell, A. Adegnika, G. Mombo-Ngoma, M. Ramharter   +15 more
semanticscholar   +1 more source

Identification and characterization of Loa loa antigens responsible for cross-reactivity with rapid diagnostic tests for lymphatic filariasis.

PLoS Neglected Tropical Diseases, 2018
The Global Program to Eliminate Lymphatic Filariasis (LF) relies on rapid diagnostic tests (RDTs) to determine where annual mass drug administration for LF is required and when it can be stopped.
Marla I Hertz, Hugues Nana-Djeunga, Joseph Kamgno, Abdel Jelil Njouendou, Valerine Chawa Chunda, Samuel Wanji, Amy Rush, Peter U Fischer, Gary J Weil, Philip J Budge   +9 more
doaj   +1 more source

Recurring Transient Tooth Pain as Newly Described Symptom of Migratory Loiasis: A Mixed-Methods Study in Rural Gabon. [PDF]

Am J Trop Med Hyg
. Loiasis, a filarial pathogen exclusively endemic in central and western Africa, causes a wide spectrum of symptoms. Understanding the breadth of its clinical manifestations is of importance for adequate patient care and to understand its disease burden.
Hildebrandt TR, Ramharter H, Lumeka Kabwende A, Endamne L, Davi SD, Adegnika AA, Mombo-Ngoma G, Agnandji ST, Mischlinger J, Manego Zoleko R, Ramharter M.   +10 more
europepmc   +2 more sources

Linear epitopes in Onchocerca volvulus vaccine candidate proteins and excretory‐secretory proteins

Parasite Immunology, Volume 40, Issue 11, November 2018., 2018
Summary In our previous study, a proteome‐wide screen was conducted to identify linear epitopes in this parasite's proteome, resulting in the discovery of three immunodominant motifs. Here, we investigated whether such antigenic peptides were found in proteins that were already known as vaccine candidates and excretome/secretome proteins for Onchocerca
Ole Lagatie, Ann Verheyen, Bieke Van Dorst, Linda Batsa Debrah, Alex Debrah, Lieven J. Stuyver   +5 more
wiley   +1 more source