Results 31 to 40 of about 1,188 (111)
Parasites & Vectors, 2014 Background The wide distribution of Loa loa infection (loiasis) throughout the Democratic Republic of Congo (DRC) is a major obstacle to the plans to eliminate onchocerciasis and lymphatic filariasis (LF) because the standard drug regime is dependent on ...
Louise A Kelly-Hope +4 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2018 The Global Program to Eliminate Lymphatic Filariasis (LF) relies on rapid diagnostic tests (RDTs) to determine where annual mass drug administration for LF is required and when it can be stopped.
Marla I Hertz +9 more
doaj +1 more source
Linear epitopes in Onchocerca volvulus vaccine candidate proteins and excretory‐secretory proteins
Parasite Immunology, Volume 40, Issue 11, November 2018., 2018 Summary In our previous study, a proteome‐wide screen was conducted to identify linear epitopes in this parasite's proteome, resulting in the discovery of three immunodominant motifs. Here, we investigated whether such antigenic peptides were found in proteins that were already known as vaccine candidates and excretome/secretome proteins for Onchocerca
Ole Lagatie +5 more
wiley +1 more source
The Bidirectional Relationship between Sleep and Immunity against Infections
Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015 Sleep is considered an important modulator of the immune response. Thus, a lack of sleep can weaken immunity, increasing organism susceptibility to infection. For instance, shorter sleep durations are associated with a rise in suffering from the common cold.
Elizabeth G. Ibarra-Coronado +8 more
wiley +1 more source
International Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013 This work was aimed at determining the epidemiological implications of deer fly biting in Southeastern Nigeria and ascertaining the circadian and monthly biting pattern and the transmission potential of Chrysops in the area. Human‐landing catches were carried out for 52 weeks by a catching team of four. A total of 930 female Chrysops sp.
Emmanuel Chukwunenye Uttah +3 more
wiley +1 more source
Effect of a single dose (600 mg) of albendazole on Loa loa microfilaraemia
Parasite, 2002 The problem of Loa encephalopathy, which may occur after ivermectin treatment of patients harbouring high Loa microfilarial loads, might be solved if one could find a treatment regimen bringing about a significant but progressive decrease in the Loa ...
Kamgno J., Boussinesq M.
doaj +1 more source
Ophthalmic Parasitosis: A Review Article
Interdisciplinary Perspectives on Infectious Diseases, Volume 2012, Issue 1, 2012., 2012 Ocular parasitosis in human is more prevalent in geographical areas where environmental factors and poor sanitary conditions favor the parasitism between man and animals. Lesions in the eye can be due to damage directly caused by the infectious pathogen, indirect pathology caused by toxic products, or the immune response incited by infections or ...
Amal R. Nimir +3 more
wiley +1 more source
Parasites & Vectors, 2012 Background A simple method called RAPLOA, to rapidly assess what proportion of people in a community are infected with L. loa and hence which communities are at high risk of severe adverse reactions following ivermectin treatment, was developed in ...
Wanji Samuel +6 more
doaj +1 more source
Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management
Journal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz +3 more
wiley +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
Pest Management Science, Volume 81, Issue 7, Page 3956-3983, July 2025.The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier +26 more
wiley +1 more source