Results 91 to 100 of about 823,716 (355)
Debate on long-acting β agonists for asthma:they think it's all over [PDF]
, 2017 At last, we can apparently relax in the secure knowledge that long-acting β agonists (LABA) are safe to use in persistent asthma when given in combination with inhaled corticosteroid (ICS), on the basis of the US Food and Drug Administration-mandated ...Bleecker, Drake, Lee, Lipworth, Lipworth, Pauwels, Peters, Stempel, Tan, Thanawala, Thomas, Turner +11 morecore +2 more sourcesMapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI) Dong‐Woo Shin, Tingting Chen, James A. Letts +2 morewiley +1 more sourceA US Retrospective Claims Analysis Comparing Healthcare Costs of Patients Transitioning from Immediate-Release Oxycodone to Two Different Formulations of Extended-Release Oxycodone: Xtampza ER or OxyContin
ClinicoEconomics and Outcomes Research, 2022 Oluwadara Olatoke,1 Vladimir Zah,1 Filip Stanicic,1 Djurdja Vukicevic,1 Platonas Yfantopoulos,1 Christy Thompson,2 Michael K DeGeorge,2 Steven Passik2 1HEOR Department, ZRx Outcomes Research, Mississauga, Ontario, Canada; 2Medical Department, Collegium ...Olatoke O, Zah V, Stanicic F, Vukicevic D, Yfantopoulos P, Thompson C, DeGeorge MK, Passik S +7 moredoaj Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. [PDF]
, 2014 BACKGROUND: Pharmacological therapy for chronic obstructive pulmonary disease (COPD) is aimed at relieving symptoms, improving quality of life and preventing or treating exacerbations.Treatment tends to begin with one inhaler, and additional therapies ...Aalbers, Abrahams, Abrahams, Adams, Agusti, Allegra, Ambrosino, Amgott, Anderson, Anonymous, Anthonisen, Antoniu, Anzueto, Anzueto, Appleton, Arievich, Auffarth, Bale, Barnes, Barnes, Barnes, Barr, Bateman, Bateman, Bateman, Bateman, Bateman, Bateman, Bateman, Bateman, Bateman, Baumgartner, Beeh, Beeh, Beeh, Berger, Bleecker, Bleecker, Bleecker, Bogdan, Bogdan, Bourbeau, Bourbeau, Braido, Briggs, Briggs, Briggs, Briggs, Brightling, Brusasco, Brusasco, Buhl, Buhl, Burge, Burge, Burge, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley PMA (on behalf of the Symbicort® study group), Calverly, Calverly, Campbell, Campbell, Casaburi, Cazzola, Cazzola, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Chan, Chapman, Chavannes, Chavannes, Chavannes, Chong, Choudhury, Chuck, Cipriani, Claverley, Cooper, Cooper, Cooper, Cooper, Cope, Cope, Corhay, Corhay, Covelli, Crim, Culpitt, D'Amato, D'Urzo, D'Urzo, D'Urzo, D'Urzo, D'Urzo, D'Urzo, Dahl, Dahl, Dahl, Dahl, Dahl, Dahl, Dahl, Dal Negro, Dal Negro, Dalal, Dalal, Dawber, Decramer, Decramer, Decramer, Decramer, Decramer, Decramer, Decramer, Decramer, Decramer, Decramer, Derenne, Dias, Dias, Dias, DiSantostefano, Doherty, Doherty, Doherty, Doherty, Dong, Donohue, Donohue, Donohue, Donohue, Donohue, Dransfield, Dunn, Dusser, Dusser, Dusser, Earnshaw, Eden, Edin, Effing, Eichenhorn, Fang, Fattore, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferreira, Freeman, Freeman, Friedman, Frith, Fukuchi, Fukuchi, Geake, Gelb, Gizycki, Glaab, Greefhorst, Greefhorst, Greefhorst, Gross, Grunsven, Grunsven, Guenette, Halpin, Halpin, Halpin, Hanania, Hanania, Hanania, Hanania, Hanrahan, Hanrahan, Hanrahan, Hanrahan, Hanrahan, Hattotuwa, Hettle, Hodder, Hogan, Hoogendoorn, Horstman, Houghton, Hunjan, Hunjan, Hutchinson, Inoue, Janssens, Jarad, Jenkins, Jenkins, Johansson, John, Johnell, Johnson, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Kaptein, Kardos, Kardos, Karner, Karner, Karner, Karner, Kato, Keene, Kerstjens, Kerstjens, Kerstjens, Kerstjens, Kerstjens, Kerstjens, Kerwin, Kerwin, Kerwin, Kerwin, Kerwin, Kerwin, Kesten, Kesten, Kesten, Kew, Kew, Khamis, Korenblat, Kornmann, Kornmann, Kristufek, Kristufek, Kristufek, Kunz, Lacasse, Langley, Lapperre, Laties, Littner, Llewellyn-Jones, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Loke, Loppow, Lu, Lung Health Study Research Group, Löfdahl, Magnussen, Mahler, Mahler, Mahler, Mahler, Mahler, Mahler, Mahler, Mahler, Mahmud, Martinez, Matiz-Bueno, Matiz-Bueno, McDonough, McGarvey, McGarvey, McGarvey, Meer Regina, Mirici, Moen, Moita, Moita, Morice, Morice, Nannini, Nannini, Nannini, Nelson, Nelson, Nelson, Nelson, Nelson, Niewoehner, Niewoehner, Nishimura, Nitschmann, Noppen, O'Donnell, Ohar, Osztovits, Overbeek, Ozol, Ozol, Paggiaro, Paggiaro, Paggiaro, Paggiaro, Pauwels, Pauwels, Pauwels, Powrie, Powrie, Puhan, Puhan, Qiu, Qiu, Rabe, Renkema, Renkema, Rennard, Rennard, Rennard, Rennard, Rennard, Rennard, Rennard, Rennard, Rice, Rizzato, Robertson, Rodrigo, Rodrigo, Rodriguez Gonzalez-Moro, Rossi, Rutgers, Rutten-van Molken, Rutten-van Molken, Rutten-van Mölken, Rutten-van Mölken, Rutten-van Mölken, Sacchetta, Scanlon, Schermer, Sciurba, Sciurba, Scott, Scott, Seemungal, Seemungal, Senderovitz, Senderovitz, Serby, Sestini, Shaker, Shaker, Sharafkhaneh, Sharafkhaneh, Sharafkhaneh, Sin, Sin, Singh, Singh, Singh, Southard, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spiegelhalter, Stockley, Sun, Szafranski, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Thompson, Thompson, To, Tonnei, Tonnel, Troosters, Troosters, Valk, Verhoeven, Verhoeven, Verhoeven, Verhoeven, Verhoeven, Verkindre, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vogelmeier, Vogelmeier, Vogelmeier, Vogelmeier, Vogelmeier, Vogelmeier, Voshaar, Voshaar, Wadbo, Watkins, Wedzicha, Wedzicha, Wedzicha, Wedzicha, Wedzicha, Weel, Weiner, Weiner, Weir, Weir, Weir, Weir, Welsh, Welte, Welte, Welte, Welte, Welte, Wempe, Wouters, Yan, Yang, Yildiz, Zaniolo, Zheng, Zheng, Zhong, Zhong, Zhong, Zu Wallack, ZuWallack +511 morecore +1 more sourceEnteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld +5 morewiley +1 more sourceLong-term survival outcomes associated with inhalation therapy in chronic obstructive pulmonary disease: a 5-year multicenter prospective cohort study
European Journal of Medical ResearchBackground Chronic obstructive pulmonary disease (COPD) represents a significant global health challenge, characterized by high mortality rates. While inhalation therapies, specifically long-acting bronchodilators (LABD) and inhaled corticosteroids (ICS),Genta Akiyama, Hiroaki Ogata, Kazuya Tsubouchi, Tomotsugu Takano, Katsuyuki Ichiki, Ryo Torii, Shohei Takata, Noriaki Nakagaki, Makoto Yoshida, Yasuhiko Kitasato, Kazunori Tobino, Eiji Harada, Hiroshi Wataya, Hiroshi Ishii, Takashige Maeyama, Masayuki Kawasaki, Masaki Fujita, Kazuhiro Yatera, Yoshiaki Zaizen, Fumiaki Kiyomi, Yoichi Nakanishi, Isamu Okamoto +21 moredoaj +1 more sourcePatient-reported tolerability and acceptability of cabotegravir + rilpivirine long-acting injections for the treatment of HIV-1 infection: 96-week results from the randomized LATTE-2 study
HIV Research & Clinical Practice, 2019 Background: Long-acting (LA) injectable antiretroviral therapy (ART) is a novel modality currently under development as an alternative to daily oral ART. Objective: The LATTE-2 study (ClinicalTrials.gov identifier NCT02120352) showed that cabotegravir LA Miranda Murray, Federico Pulido, Anthony Mills, Moti Ramgopal, Roger LeBlanc, Hans Jaeger, Viviam Canon, David Dorey, Sandy Griffith, Joseph Mrus, William Spreen, David Margolis +11 moredoaj +1 more sourceA Potential Long-Acting LDL-Cholesterol–Lowering PCSK9 Monoclonal Antibody
, 2021 Yimin Cui, Xia Zhao, Litong Qi, Xin Li, Zhijun Huang, Guoping Yang, Lei Qian, Huan Deng, Haoyu Li, Yong Huo +9 moreopenalex +1 more source