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Update on Long-Acting Anticholinergics in Children and Adolescents With Difficult and Severe Asthma [PDF]

open access: yesFrontiers in Pediatrics, 2022
Tiotropium bromide is the only long-acting muscarinic antagonist (LAMA) approved for treatment of patients aged ≥6 years old who have symptoms of uncontrolled asthma.
Francesca Santamaria   +4 more
doaj   +10 more sources

Relevance of dosage in adherence to treatment with long-acting anticholinergics in patients with COPD [PDF]

open access: yesInternational Journal of COPD, 2016
José Luis Izquierdo,1 José Manuel Paredero,2 Raul Piedra3 1Department of Pneumology, Hospital Universitario de Guadalajara, 2Department of Pharmacy, 3Department of Primary Care, Guadalajara Integrated Care Management, Guadalajara, Spain ...
Izquierdo JL, Paredero JM, Piedra R
doaj   +10 more sources

Bronchodilator treatment of stable COPD: long-acting anticholinergics [PDF]

open access: yesEuropean Respiratory Review, 2005
Since airflow obstruction in chronic obstructive pulmonary disease (COPD) is to some extent reversible, bronchodilators play an important role in the maintenance treatment of COPD the more they reduce hyperinflation and, as a result, improve dyspnoea and
W. Vincken
doaj   +6 more sources

Inhaled Long-acting Anticholinergics and Urinary Tract Infection in Individuals with COPD

open access: yesCOPD: Journal of Chronic Obstructive Pulmonary Disease, 2017
Inhaled, long-acting anticholinergic medication (LAA), commonly used for moderate-to-severe chronic obstructive pulmonary disease (COPD), has been shown to decrease COPD hospitalizations, emergency department visits, and acute exacerbations but has also ...
Andrea S Gershon   +2 more
exaly   +5 more sources

Adherence and Persistence to Long-Acting Anticholinergics Treatment Episodes in Patients With Chronic Obstructive Pulmonary Disease

open access: yesAnnals of Pharmacotherapy, 2017
Background:No studies have examined adherence or persistence to long-acting anticholinergics (LAAC) treatment episodes in patients with chronic obstructive pulmonary disease (COPD).
Marie-France Beauchesne   +2 more
exaly   +5 more sources

Long-acting muscarinic antagonists: a potential add-on therapy in the treatment of asthma? [PDF]

open access: yesEuropean Respiratory Review, 2016
Asthma is a chronic inflammatory disorder of the airways that is a major global burden on both individuals and healthcare systems. Despite guideline-directed treatment, a significant proportion of patients with asthma do not achieve control.
William W. Busse   +3 more
doaj   +3 more sources

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis. [PDF]

open access: yesCochrane Database of Systematic Reviews, 2014
BACKGROUND: Pharmacological therapy for chronic obstructive pulmonary disease (COPD) is aimed at relieving symptoms, improving quality of life and preventing or treating exacerbations.Treatment tends to begin with one inhaler, and additional therapies ...
Christopher J Cates   +8 more
core   +6 more sources

The mode of action of anticholinergics in asthma [PDF]

open access: yesEuropean Respiratory Journal, 2018
Acetylcholine binds to muscarinic receptors to play a key role in the pathophysiology of asthma, leading to bronchoconstriction, increased mucus secretion, inflammation and airway remodelling. Anticholinergics are muscarinic receptor antagonists that are
Reinoud Gosens, Nicholas Gross
exaly   +3 more sources

The use of short-acting bronchodilators in patients with chronic bronchoobstructive pathology at the present stage

open access: yesМедицинский совет, 2021
Inhaled short-acting bronchodilators (beta-agonists and M-anticholinergics) have been used for a long time in patients with bronchoobstructive diseases, the main representatives of which are chronic obstructive pulmonary disease (COPD) and bronchial ...
K. A. Zykov   +6 more
doaj   +3 more sources

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