Towards haplotypes of blood group genes: the impact of long-read sequencing in molecular immunohematology. [PDF]
Ann Transl MedWörner L, Bugert P.
europepmc +1 more source
Non-uniform chromosomal SNP density biases sites of meiotic crossovers in Drosophila melanogaster. [PDF]
G3 (Bethesda)Hinson S +5 more
europepmc +1 more source
Beyond counting: how single-cell long-read sequencing turns transcriptome complexity into precision targets. [PDF]
Front OncolByrne A, Felton C, Stephenson W.
europepmc +1 more source
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Accelerating the Next Generation Long Read Mapping with the FPGA-Based System
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2014To compare the newly determined sequences against the subject sequences stored in the databases is a critical job in the bioinformatics. Fortunately, recent survey reports that the state-of-the-art aligners are already fast enough to handle the ultra amount of short sequence reads in the reasonable time.
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Benchmarking tools for long reads mapping
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Fast and Accurate Algorithms for Mapping and Aligning Long Reads
Journal of Computational Biology, 2021For DNA sequence analysis, we are facing challenging tasks such as the identification of structural variants, sequencing repetitive regions, and phasing of alleles. Those challenging tasks suffer from the short length of sequencing reads, where each read may cover less than 2 single nucleotide polymorphism (SNP), or less than two occurrences of a ...
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Weighted syncmer sampling improves long-read mapping
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DiMeLo-seq: a long-read, single-molecule method for mapping protein–DNA interactions genome wide [PDF]
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An Efficient Parallel Sketch-Based Algorithmic Workflow for Mapping Long Reads
IEEE Transactions on Computational Biology and Bioinformatics, 20231 Abstract Long read technologies are continuing to evolve at a rapid pace, with the latest of the high fidelity technologies delivering reads over 10Kbp with high accuracy (99.9%). Classical long read assemblers produce assemblies directly from long reads.
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Ultra-fast and High-quality Mapping of Error-prone Long Reads
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