Results 51 to 60 of about 296,746 (277)
Mapping-based genome size estimation
BMC GenomicsWhile the size of chromosomes can be measured under a microscope, obtaining the exact size of a genome remains a challenge. Biochemical methods and k-mer distribution-based approaches allow only estimations. An alternative approach to estimate the genome
Shakunthala Natarajan +2 more
doaj +1 more source
A new hash function and its use in read mapping on genome [PDF]
AUT Journal of Mathematics and Computing, 2020 Mapping reads onto genomes is an indispensable step in sequencing data analysis. A widely used method to speed up mapping is to index a genome by a hash table, in which genomic positions of $k$-mers are stored in the table.
Farzaneh Salari +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
, 2015 Results from read mapping. Data presented from three bioinformatics workflows; MiSEQ Reporter 2.1.43 (Smith Waterman algorithm mapper), CLC Genomics Workbench 5.51 (default CLC mapper) and in-house custom pipeline (Burrows Wheeler Alignment tool).Read ...
Viktor Ljungström (778129) +5 more
core +1 more source
Wochenende — modular and flexible alignment-based shotgun metagenome analysis
BMC Genomics, 2022 Background Shotgun metagenome analysis provides a robust and verifiable method for comprehensive microbiome analysis of fungal, viral, archaeal and bacterial taxonomy, particularly with regard to visualization of read mapping location, normalization ...
Ilona Rosenboom +12 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Maptcha: an efficient parallel workflow for hybrid genome scaffolding
BMC BioinformaticsBackground Genome assembly, which involves reconstructing a target genome, relies on scaffolding methods to organize and link partially assembled fragments. The rapid evolution of long read sequencing technologies toward more accurate long reads, coupled
Oieswarya Bhowmik +2 more
doaj +1 more source