Results 151 to 160 of about 543,035 (258)

Conditional deletion of TRPC1 channel modulates synaptic plasticity, long term depression, and memory extinction in Fragile X syndrome mice. [PDF]

iScience
Issa F, Yerna X, Parpaite T, Jabbour C, Schakman O, Tajeddine N, Gualdani R, Gailly P.   +7 more
europepmc   +1 more source

Long-Term Depression of Striatal DA Release Induced by mGluRs via Sustained Hyperactivity of Local Cholinergic Interneurons. [PDF]

Front Cell Neurosci, 2021
Mercuri NB, Federici M, Rizzo FR, Maugeri L, D'Addario SL, Ventura R, Berretta N.   +6 more
europepmc   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

Three-day delta-9-tetrahydrocannabinol (THC) exposure eliminates long-term depression in ventral tegmental area of young, but not adult mice. [PDF]

J Cannabis Res
Von Gunten M, Hoffman S, Smartt A, Edwards JG.   +3 more
europepmc   +1 more source

Repeated inhibition of sigma-1 receptor suppresses GABA_A receptor expression and long-term depression in the nucleus accumbens leading to depressive-like behaviors. [PDF]

Front Mol Neurosci, 2022
Qin Y, Xu W, Li K, Luo Q, Chen X, Wang Y, Chen L, Sha S.   +7 more
europepmc   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Corrigendum: Contribution of thyrotropin-releasing hormone to cerebellar long-term depression and motor learning. [PDF]

Front Cell Neurosci
Watanave M, Matsuzaki Y, Nakajima Y, Ozawa A, Yamada M, Hirai H.   +5 more
europepmc   +1 more source

Age-Dependent Contributions of NMDA Receptors and L-Type Calcium Channels to Long-Term Depression in the Piriform Cortex. [PDF]

Int J Mol Sci, 2021
Rajani V, Maziar A, Man KNM, Hell JW, Yuan Q.   +4 more
europepmc   +1 more source

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Cortical Tagged Synaptic Long-Term Depression in the Anterior Cingulate Cortex of Adult Mice. [PDF]

J Neurosci
Liu W, Chen QY, Li XH, Zhou Z, Zhuo M.
europepmc   +1 more source