Results 51 to 60 of about 4,590,611 (322)

A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity

open access: yesFrontiers in Synaptic Neuroscience, 2021
Neuromodulation can profoundly impact the gain and polarity of postsynaptic changes in Hebbian synaptic plasticity. An emerging pattern observed in multiple central synapses is a pull–push type of control in which activation of receptors coupled to the G-
Stefan Mihalas   +5 more
doaj   +1 more source

Examining Children’s Cognitions in Response to Interparental Conflict [PDF]

open access: yes, 2017
Extensive research has found that interparental conflict is associated with children’s adjustment and cognitive appraisals. This study aims to address two questions.
Portnoy, Madeline M
core   +1 more source

Medial Superior Olivary Neurons Receive Surprisingly Few Excitatory and Inhibitory Inputs with Balanced Strength and Short-Term Dynamics [PDF]

open access: yes, 2010
Neurons in the medial superior olive (MSO) process microsecond interaural time differences, the major cue for localizing low-frequency sounds, by comparing the relative arrival time of binaural, glutamatergic excitatory inputs. This coincidence detection
Couchman, Kiri   +2 more
core   +2 more sources

Delirium, depression, and long-term cognition

open access: yesInternational Psychogeriatrics, 2023
We examined whether preadmission history of depression is associated with less delirium/coma-free (DCF) days, worse 1-year depression severity and cognitive impairment.A health proxy reported history of depression. Separate models examined the effect of preadmission history of depression on: (a) intensive care unit (ICU) course, measured as DCF days ...
Patricia S. Andrews   +9 more
openaire   +2 more sources

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell   +8 more
wiley   +1 more source

The demise of the synapse as the locus of memory: A looming paradigm shift?

open access: yesFrontiers in Systems Neuroscience, 2016
Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognised. From the perspective of what we might call
Patrick C. Trettenbrein   +1 more
doaj   +1 more source

Psychotherapies for depression: a network meta‐analysis covering efficacy, acceptability and long‐term outcomes of all main treatment types

open access: yesWorld Psychiatry, 2021
The effects of psychotherapies for depression have been examined in several hundreds of randomized trials, but no recent network meta‐analysis (NMA) has integrated the results of these studies.
P. Cuijpers   +8 more
semanticscholar   +1 more source

How much improvement in mental health can be expected when people stop smoking? Findings from a national survey [PDF]

open access: yes, 2015
Background and aims: There is evidence that mental health improves when smokers stop. This study aimed to assess in a nationally representative sample how far anxiety and depression in long-term ex-smokers can be expected eventually to reach levels found
Brown, J   +4 more
core  

Aging, Cognitive Decline and Hearing Loss: Effects of Auditory Rehabilitation and Training with Hearing Aids and Cochlear Implants on Cognitive Function and Depression among Older Adults [PDF]

open access: yes, 2016
A growing interest in cognitive effects associated with speech and hearing processes is spreading throughout the scientific community essentially guided by evidence that central and peripheral hearing loss is associated with cognitive decline.
Benatti, Alice   +10 more
core   +1 more source

Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]

open access: yesScientific Reports, 2016
AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
G. Antunes   +2 more
openaire   +2 more sources

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