Results 51 to 60 of about 4,235,672 (400)
The demise of the synapse as the locus of memory: A looming paradigm shift?
Frontiers in Systems Neuroscience, 2016 Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognised. From the perspective of what we might call
Patrick C. Trettenbrein +1 more
doaj +1 more source
The long-term effects of ABM on symptom severity in patients with recurrent depression: A randomized sham-controlled trial [PDF]
, 2023 Background: The present study reports on long-term outcomes of ABM over one year in self-reported and clinician-rated depression symptoms, anxiety symptoms, and relapse rates. Methods: We conducted a double-blind randomized sham-controlled trial in 301
Bø, Ragnhild +5 more
core +1 more source
Motor cortical plasticity induced by motor learning through mental practice.
Frontiers in Behavioral Neuroscience, 2015 Several investigations suggest that actual and mental actions trigger similar neural substrates. Motor learning via physical practice results in long-term potentiation (LTP)-like plasticity processes, namely potentiation of M1 and a temporary occlusion ...
Laura eAvanzino +5 more
doaj +1 more source
Optimizing Audio Recommendations for the Long-Term: A Reinforcement Learning Perspective [PDF]
arXiv, 2023 We present a novel podcast recommender system deployed at industrial scale. This system successfully optimizes personal listening journeys that unfold over months for hundreds of millions of listeners. In deviating from the pervasive industry practice of optimizing machine learning algorithms for short-term proxy metrics, the system substantially ...
arxiv
TIME OF DIABETIC ULCER FOOT SUFFERING AND DEPRESSION SYMPTOMS IN ULIN GENERAL HOSPITAL BANJARMASIN
Berkala Kedokteran, 2017 : Diabetic foot ulcers are one kind of chronic complication of diabetes mellitus in the form of an open wound on the skin’s surface and may be accompanied by local tissue death. Long term suffering of diabetic foot ulcers with physical and psychological
Rizka Dwi Puteri +2 more
doaj +1 more source
Towards More Efficient Depression Risk Recognition via Gait [PDF]
arXiv, 2023 Depression, a highly prevalent mental illness, affects over 280 million individuals worldwide. Early detection and timely intervention are crucial for promoting remission, preventing relapse, and alleviating the emotional and financial burdens associated with depression. However, patients with depression often go undiagnosed in the primary care setting.
arxiv
Frontiers in Cellular Neuroscience, 2015 Estrogenic and androgenic steroids synthesized in the brain may rapidly modulate synaptic plasticity interacting with specific membrane receptors. We explored by electrophysiological recordings in hippocampal slices of male rat the influence of 17b ...
Michela eDi Mauro +6 more
doaj +1 more source
A Practical Guide to Using CV Analysis for Determining the Locus of Synaptic Plasticity
Frontiers in Synaptic Neuroscience, 2020 Long-term synaptic plasticity is widely believed to underlie learning and memory in the brain. Whether plasticity is primarily expressed pre- or postsynaptically has been the subject of considerable debate for many decades. More recently, it is generally
Jennifer A. Brock +6 more
doaj +1 more source
Frontiers in Synaptic Neuroscience, 2021 Neuromodulation can profoundly impact the gain and polarity of postsynaptic changes in Hebbian synaptic plasticity. An emerging pattern observed in multiple central synapses is a pull–push type of control in which activation of receptors coupled to the G-
Stefan Mihalas +5 more
doaj +1 more source
Nature Communications, 2014 NMDA-type glutamate receptors (NMDARs) are currently regarded as paramount in the potent and selective disruption of synaptic plasticity by Alzheimer’s disease amyloid β-protein (Aβ). Non-NMDAR mechanisms remain relatively unexplored.
Neng-Wei Hu +9 more
semanticscholar +1 more source