Results 61 to 70 of about 546,199 (258)

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Research Progress on the mechanism of synaptic plasticity in acupuncture intervention for Post-Stroke depression

针刺研究
Structural and functional abnormalities in synaptic plasticity are closely related to the onset and progression of post-stroke depression （PSD）. Acupuncture has been clinically recognized for its safety and efficacy in PSD intervention.This article ...
Wang Feiyan, Li Yue, Zeng Huijuan, Lin Shengshi, Dong Chunxuan, Ma Chongbing   +5 more
doaj  

Exercise is medicine for depression: even when the “pill” is small

Neuropsychiatric Disease and Treatment, 2016
Mats Hallgren,1 Davy Vancampfort,2,3 Brendon Stubbs4,5 1Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden; 2Department of Rehabilitation Sciences, 3University Psychiatric Centre – KU Leuven, KU Leuven &ndash ...
Hallgren M, Vancampfort D, Stubbs B
doaj  

Store-Operated Calcium Entry Is Required for mGluR-Dependent Long Term Depression in Cortical Neurons

Frontiers in Cellular Neuroscience, 2017
Store-operated calcium entry (SOCE) is a Calcium (Ca2+) influx pathway activated by depletion of intracellular stores that occurs in eukaryotic cells. In neurons, the presence and functions of SOCE are still in question.
Paloma González-Sánchez, Paloma González-Sánchez, Paloma González-Sánchez, Araceli del Arco, Araceli del Arco, Araceli del Arco, José A. Esteban, Jorgina Satrústegui, Jorgina Satrústegui, Jorgina Satrústegui   +9 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Synaptic homeostasis transiently leverages Hebbian mechanisms for a multiphasic response to inactivity

Cell Reports
Summary: Homeostatic regulation of synapses is vital for nervous system function and key to understanding a range of neurological conditions. Synaptic homeostasis is proposed to operate over hours to counteract the destabilizing influence of long-term ...
Simón(e) D. Sun, Daniel Levenstein, Boxing Li, Nataniel Mandelberg, Nicolas Chenouard, Benjamin S. Suutari, Sandrine Sanchez, Guoling Tian, John Rinzel, György Buzsáki, Richard W. Tsien   +10 more
doaj   +1 more source

Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory

Nature Communications, 2019
How astrocytes influence neuronal plasticity remains unclear, as they are typically considered as modulators of core mechanisms driven by neuronal components.
Marta Navarrete, María I. Cuartero, Rocío Palenzuela, Jonathan E. Draffin, Ainoa Konomi, Irene Serra, Sandra Colié, Sergio Castaño-Castaño, Mazahir T. Hasan, Ángel R. Nebreda, José A. Esteban   +10 more
doaj   +1 more source

Duration of unemployment and depression: a cross-sectional survey in Lithuania

BMC Public Health, 2006
Background In spite of a growing economy, unemployment is still a severe socio-economic problem in Lithuania. Nonetheless, no studies have been performed about the associations between unemployment and mental health in Lithuania.
Starkuviene Skirmante, Kalediene Ramune, Stankunas Mindaugas, Kapustinskiene Violeta   +3 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source