Results 111 to 120 of about 3,075,584 (328)
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
Advanced Science, EarlyView.This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan +11 more
wiley +1 more source
The electrostatic potential of a periodic lattice [PDF]
arXiv, 2014 We calculate the electrostatic potential of a periodic lattice of arbitrary extended charges by using the Cartesian multipole formalism. This method allows the separation of the long-range potential from the contact potential (potential on the source).
arxiv
A molecular brake controls the magnitude of long-term potentiation
Nature Communications, 2014 Overexpression of suprachiasmatic nucleus circadian oscillatory protein (SCOP), a negative ERK regulator, blocks long-term memory encoding. Inhibition of calpain-mediated SCOP degradation also prevents the formation of long-term memory, suggesting rapid ...
Yubin Wang +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.Solution‐processed approach for integration of Fe2O3/WS2 nano‐hybrid composite memristor devices. Remarkable switching characteristics and excellent durability for up to 105 cycles. The device shows ultra‐low energy consumption of 0.072 pJ and excellent environmental stability.
Faisal Ghafoor +11 more
wiley +1 more source
The role of astrocytic aquaporin-4 in synaptic plasticity and learning and memory
Frontiers in Integrative Neuroscience, 2016 Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the central nervous system. AQP4 is widely expressed throughout the brain, especially at the blood-brain barrier where AQP4 is highly polarized to astrocytic foot processes ...
Jenny I. Szu, Devin K. Binder
doaj +1 more source
Quantum Ground State Energies for Very Flat Potentials [PDF]
arXiv, 2018 An infinite sequence of potential well functions is considered. A trial wavefunction is used with the Schr$\ddot{\text{o}}$dinger equation to obtain an approximate ground state energy for each potential well function. We obtain an expression that is exactly correct for the harmonic potential, has an intuitively correct form for all of our potential ...
arxiv
Philosophical Transactions of the Royal Society B: Biological Sciences, 2014 The molecular processes involved in establishing long-term potentiation (LTP) have been characterized well, but the decay of early and late LTP (E-LTP and L-LTP) is poorly understood.
Oliver Hardt, K. Nader, Yu-tian Wang
semanticscholar +1 more source
Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
Advanced Science, EarlyView.This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao +15 more
wiley +1 more source
Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease
Frontiers in Pharmacology, 2019 Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic transmission represent the principal experimental models underlying learning and memory.
Dalila Mango +7 more
doaj +1 more source
Advanced Science, EarlyView.A new strategy for constructing smart gel‐based MN patches is developed to overcome the insufficient drug delivery of eye drops to the lacrimal gland. The gel‐based MN patches achieved long‐acting drug release in a ROS‐responsive manner, and separable base in a temperature‐responsive manner.
Jingqing Mu +10 more
wiley +1 more source