Results 121 to 130 of about 3,075,584 (328)

Tiagabine improves hippocampal long-term depression in rat pups subjected to prenatal inflammation.

PLoS ONE, 2014
Maternal inflammation during pregnancy is associated with the later development of cognitive and behavioral impairment in the offspring, reminiscent of the traits of schizophrenia or autism spectrum disorders.
Aline Rideau Batista Novais, Nadine Crouzin, Mélanie Cavalier, Mathilde Boubal, Janique Guiramand, Catherine Cohen-Solal, Marie-Céleste de Jesus Ferreira, Gilles Cambonie, Michel Vignes, Gérard Barbanel   +9 more
doaj   +1 more source

Enhancement of long-term potentiation by cis-unsaturated fatty acid: relation to protein kinase C and phospholipase A2 [PDF]

, 1987
DJ Linden, F.-S. Sheu, Kentaro Murakami, Aryeh Routtenberg   +3 more
openalex   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

The demise of the synapse as the locus of memory: A looming paradigm shift?

Frontiers in Systems Neuroscience, 2016
Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognised. From the perspective of what we might call
Patrick C. Trettenbrein, Patrick C. Trettenbrein   +1 more
doaj   +1 more source

Navigation Functions for Convex Potentials in a Space with Convex Obstacles [PDF]

arXiv, 2016
Given a convex potential in a space with convex obstacles, an artificial potential is used to navigate to the minimum of the natural potential while avoiding collisions. The artificial potential combines the natural potential with potentials that repel the agent from the border of the obstacles. This is a popular approach to navigation problems because
arxiv  

Elevation of intracellular calcium content in area CA1 of hippocampus is not directly correlated with the development of long-term potentiation [PDF]

, 1989
L. Siklós, U. Kuhnt, András Mihály, Ferenc Joó   +3 more
openalex   +1 more source

Differential Roles of NR2A and NR2B-Containing NMDA Receptors in Cortical Long-Term Potentiation and Long-Term Depression

Journal of Neuroscience, 2004
It is widely believed that long-term depression (LTD) and its counterpart, long-term potentiation (LTP), involve mechanisms that are crucial for learning and memory. However, LTD is difficult to induce in adult cortex for reasons that are not known. Here
P. Massey, Ben Johnson, P. Moult, Y. Auberson, Malcolm W. Brown, E. Molnár, G. Collingridge, Z. Bashir   +7 more
semanticscholar   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source

Comparing the Efficacy of Escitalopram with and without Crocin in Restoring I/O Functions and LTP within the Hippocampal CA1 Region of Stressed Rats

Advanced Biomedical Research
Background: Escitalopram, a pharmacological compound, and crocin, the active compound of saffron, influence brain functions and serotonin levels. This study examined the efficacy of escitalopram with and without crocin in restoring the input-output (I/O)
Mehran Joodaki, Maryam Radahmadi, Hojjatallah Alaei   +2 more
doaj   +1 more source

Effect of Clenbuterol Administration into the Basolateral Amygdala on Synaptic Plasticity in Dentate Gyrus Granule Cells in Male Rats

Journal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Neural circuits and neurotransmitter systems within the basolateral amygdala (BLA) play roles in forming emotional memory through communication with the hippocampus.
Seyedeh Kebria Noorani, Vida Hojati, Motahareh Rouhi Ardeshiri, Esmaeil Akbari   +3 more
doaj