Results 131 to 140 of about 82,808 (286)

NMDA and kainate receptor expression, long-term potentiation, and neurogenesis in the hippocampus of long-lived Ames dwarf mice [PDF]

, 2011
Sunita Sharma, Diane C. Darland, Saobo Lei, Sharlene Rakoczy, Holly M. Brown‐Borg   +4 more
openalex   +1 more source

Realgar‐Induced CNS Toxicity: Exploring OTC‐Mediated Ornithine Regulation of ZBTB7A Inhibits Astrocyte Glycolysis Based on the Liver–Brain Axis

Advanced Science, EarlyView.
Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ping Ye, Zhen Li, Huanyong Fu, Shuai Wang, Xingang Cui, Chengbo Song, Chao Ma, Hong Jiang   +7 more
wiley   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Polyadenylation landscape of in vivo long-term potentiation in the rat brain. [PDF]

RNA
Gumińska N, Pauzin FP, Kuźniewska B, Miłek J, Wardaszka-Pianka P, Krawczyk PS, Mroczek S, Jeleń S, Pagenhart PU, Bramham CR, Dziembowski A, Dziembowska M.   +11 more
europepmc   +1 more source

Endogenously released ACh and exogenous nicotine differentially facilitate long‐term potentiation induction in the hippocampal CA1 region of mice

, 2012
Sakura Nakauchi, Katumi Sumikawa
openalex   +2 more sources

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Long-term potentiation and neurotransmitters expression and segregation are altered in the Metabolic Syndrome-associated dysautonomia. [PDF]

PLoS One
Elinos D, Veladiz-Gracia F, González-Sierra C, Rubio-Galicia A, Cifuentes F, Morales MA.   +5 more
europepmc   +1 more source

Enhanced Hippocampal Long-Term Potentiation and Spatial Learning in Aged 11β-Hydroxysteroid Dehydrogenase Type 1 Knock-Out Mice [PDF]

, 2007
Joyce L.W. Yau, Kara McNair, June Noble, David G. Brownstein, Carina Hibberd, Nik Morton, John J. Mullins, Richard Morris, Stuart Cobb, Jonathan R. Seckl   +9 more
openalex   +1 more source

Experimental data for "Long-term potentiation mechanism of biological postsynaptic activity in neuro-inspired halide perovskite memristors"

, 2023
Enrique Hernández Balaguera, Laura Muñoz Díaz, Agustín Bou, Beatriz Romero, B.R. Ilyassov, Antonio Guerrero, Juan Bisquert   +6 more
openalex   +1 more source

Stimuli‐Responsive CuFeTe2 Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu, Jian Zheng, Mengqi Yu, Qirui Wang, Yi Yuan, Nannan Shao, Xiaoliang Yang, Tianxi Shen, Li Wang, Aiyun Li, Rui Liu, Jimin Cao, Xi Liu, Fangfang Cao, Yanlin Feng   +14 more
wiley   +1 more source