Results 131 to 140 of about 81,804 (294)

Endogenous Activation of μ and δ-1 Opioid Receptors Is Required for Long-Term Potentiation Induction in the Lateral Perforant Path: Dependence on GABAergic Inhibition [PDF]

, 1996
Clive R. Bramham, John M. Sarvey
openalex   +1 more source

Single‐Cell Transcriptomics Unravels Growth Factor Erv1‐Like Mediated Ferroptosis as a Key Driver of Intestinal Epithelial Dysfunction in Ulcerative Colitis

Advanced Science, EarlyView.
Single‐cell transcriptomic profiling of ulcerative colitis (UC) tissues identified downregulation of GFER in intestinal epithelial cells. Mechanistically, GFER interacts with PCBP1 to help maintain intracellular iron homeostasis and may also reduce lipid peroxidation by activating the PGC‐1α/PPARγ signaling pathway, thereby inhibiting ferroptosis ...
Ya Song, Fangyan Tan, Qian Song, Xiaohui Liao, Zhechuan Mei, Lin Lv   +5 more
wiley   +1 more source

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Protein synthesis-dependent formation of protein kinase Mzeta in long- term potentiation [PDF]

, 1996
Pavel Osten, L Valsamis, Alexander Z. Harris, TC Sacktor   +3 more
openalex   +1 more source

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

Advanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang, Mengdi Liang, Jing Zhang, Hua Tong, Fenfen Zhang, Ying Liu, Pui Wang, Mengmeng Chang, Fei Han, Siwen Liu, Yongping Lin, Wenjun Song, Rajendra Karki, Peihui Wang, Honglin Chen, Yang Liu, Min Zheng   +16 more
wiley   +1 more source

Vitiligo Signature‐Based Drug Screening Identifies Fulvestrant as a Novel Immunotherapy Combination Strategy

Advanced Science, EarlyView.
A vitiligo‐derived gene signature predicts response to immune checkpoint blockade across multiple cancer cohorts, providing a framework for patient stratification. Building on this, Fulvestrant—a clinically approved estrogen receptor degrader—further enhances antitumor immunity by reprogramming tumor‐associated macrophages and promoting CD8⁺ T cell ...
Jie Zhu, Liting Huang, Suzhen Bi, WeiKaixin Kong, Wanting Feng, Yingjia Li, Zhengwei Xie, Peipei Shan, Sujie Zhu   +8 more
wiley   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Regulation of Ischemic Long-Term Potentiation in GluN2B and FKBP51 Underlying Cathodal Direct Current Stimulation. [PDF]

Neurochem Res
Lee CW, Tang CW, Chang CH, Chia CM, Hsieh TH, Chi H, Lin HC.   +6 more
europepmc   +1 more source

Roles of ATP and adenosine derivatives for frequency-dependent changes of synaptic connections, long-term potentiation(LTP) and long-term depression(LTD).

, 1990
Yoichiro Kuroda
openalex   +2 more sources

Pretraining Prevents Spatial Learning Impairment after Saturation of Hippocampal Long-Term Potentiation [PDF]

, 1999
Mona K. Otnæss, Vegard Heimly Brun, May‐Britt Moser, Edvard I Moser   +3 more
openalex   +1 more source