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Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan   +7 more
wiley   +1 more source

Long-Term Synaptic Potentiation [PDF]

open access: possibleScience, 1988
Long-term synaptic potentiation (LTP) is a leading candidate for a synaptic mechanism of rapid learning in mammals. LTP is a persistent increase in synaptic efficacy that can be quickly induced. The biophysical process that controls one type of LTP is formally similar to a synaptic memory mechanism postulated decades ago by the ...
Claude L. Keenan   +3 more
openaire   +2 more sources
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Long-Term Potentiation

Annual Review of Neuroscience, 1987
History and Definition In 1973, two reports appeared in the Journal of Physiology that described a long-term potentiation (L TP) of synaptic transmission at a monosynaptic junction in the mammalian eNS. These two papers, one dealing with the anesthetized rabbit preparation (Bliss & L0mo 1973) and the other dealing with the unanesthetized rabbit (Bliss &
T J Teyler, P DiScenna
openaire   +3 more sources

The long-term potential of LTP [PDF]

open access: possibleNature Reviews Neuroscience, 2003
Long-term potentiation has captured the attention of neuroscientists for over two decades. It has provided motivation to investigate the detailed mechanisms of synaptic transmission and remains a prime candidate for mediating circuit modifications during development and experience-dependent plasticity.
openaire   +2 more sources

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