Results 71 to 80 of about 81,804 (294)

Long-term potentiation and the ageing brain

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract Ageing is associated with learning and memory impairments. Data are reviewed that suggest that age-related impairments of hippocampal-dependent forms of memory, may be caused, in part, by altered synaptic plasticity mechanisms in the hippocampus, including long-term potentiation (LTP).
openaire   +3 more sources

Challenges and Opportunities of Upconversion Nanoparticles for Emerging NIR Optoelectronic Devices

open access: yesAdvanced Materials, EarlyView.
The special photo‐responsiveness of upconversion nanoparticles has opened up a new path for the advancement of near‐infrared (NIR)‐responsive optoelectronics. However, challenges such as low energy‐conversion efficiency and high nonradiative losses still persist.
Sunyingyue Geng   +7 more
wiley   +1 more source

Effect of Clenbuterol Administration into the Basolateral Amygdala on Synaptic Plasticity in Dentate Gyrus Granule Cells in Male Rats

open access: yesJournal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Neural circuits and neurotransmitter systems within the basolateral amygdala (BLA) play roles in forming emotional memory through communication with the hippocampus.
Seyedeh Kebria Noorani   +3 more
doaj  

Depotentiation from potentiated synaptic strength in a tristable system of coupled phosphatase and kinase

open access: yesFrontiers in Computational Neuroscience, 2016
Long-term potentiation (LTP) of synaptic strength is strongly implicated in learning and memory. On the other hand, depotentiation, the reversal of synaptic strength from potentiated LTP state to the pre-LTP level, is required in extinction of the ...
Mengjiao Chen, Wei Ren, Xingang Wang
doaj   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

open access: yesAdvanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai   +6 more
wiley   +1 more source

Role of Amorphous Phases in Mixed Conduction of Conjugated Regioblock Copolymers for Organic Electrochemical Synaptic Transistors

open access: yesAdvanced Materials, EarlyView.
Critical roles of amorphous and crystalline phases in polymer‐based mixed ionic‐electronic conductors for organic electrochemical synaptic transistors using conjugated regioregular‐block‐regiorandom copolymers are demonstrated. Amorphous phases contribute to gradual polaron formation and strong ion trapping by bipolarons, leading to improved synaptic ...
Kwang‐Hun Choi   +10 more
wiley   +1 more source

Tiagabine improves hippocampal long-term depression in rat pups subjected to prenatal inflammation.

open access: yesPLoS ONE, 2014
Maternal inflammation during pregnancy is associated with the later development of cognitive and behavioral impairment in the offspring, reminiscent of the traits of schizophrenia or autism spectrum disorders.
Aline Rideau Batista Novais   +9 more
doaj   +1 more source

Frequency Switching Neuristor for Realizing Intrinsic Plasticity and Enabling Robust Neuromorphic Computing

open access: yesAdvanced Materials, EarlyView.
A frequency switching (FS) neuristor is proposed, comprising a Mott memristor and a valence change mechanism (VCM) memristor. The FS neuristor exhibits a multi‐level frequency–voltage (f–V) characteristics, enabling the implementation of neuronal intrinsic plasticity transfer functions.
Woojoon Park   +12 more
wiley   +1 more source

Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

open access: yesFrontiers in Pharmacology, 2019
Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic transmission represent the principal experimental models underlying learning and memory.
Dalila Mango   +7 more
doaj   +1 more source

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