Results 81 to 90 of about 3,183,091 (359)

Long-term potentiation-based screening identifies neuronal PYGM as a synaptic plasticity regulator participating in Alzheimer’s disease [PDF]

, 2023
Ting Wang, Yun-Qiang Zhou, Yong Wang, Liang Zhang, Xiang Zhu, Xiuyan Wang, Jinghui Wang, Lin-Kun Han, Jian Meng, Xian Zhang, Hong Luo, Qilin Ma, Zhanxiang Wang, Yun‐wu Zhang, Yun-Wu Zhang, 厦门大学附属第一医院福建省脑科疾病临床医学研究中心, 福建 厦门 361003, 中国   +15 more
openalex   +1 more source

β-Adrenergic receptor signaling and modulation of long-term potentiation in the mammalian hippocampus

Learning & memory (Cold Spring Harbor, N.Y.), 2015
Encoding new information in the brain requires changes in synaptic strength. Neuromodulatory transmitters can facilitate synaptic plasticity by modifying the actions and expression of specific signaling cascades, transmitter receptors and their ...
T. O’Dell, Steven A. Connor, Ryan Guglietta, P. Nguyen   +3 more
semanticscholar   +1 more source

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source

Promoting neurological recovery of function via metaplasticity [PDF]

, 2010
The modification of synapses by neural activity has been proposed to be the substrate for experience-dependent brain development, learning, and recovery of visual function after brain injury.
Abraham, Abraham, Barria, Bear, Bienenstock, Blais, Chen, Cho, Clothiaux, Gardoni, Hamada, Iezzi, Kathleen KA Cho, Kirkwood, Kirkwood, Kuo, Laurie, Mark F Bear, Mioche, Perez-Otano, Philpot, Philpot, Philpot, Priestley, Quinlan, Quinlan, Sans, Sato, Sheng, Smith, Sobczyk, Steigerwald, Thickbroom, Todd, Vicini, Vissel, Watanabe, Wiesel, Xu, Yoshii   +39 more
core   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Ammonia-mediated LTP inhibition: Effects of NMDA receptor antagonists and l-carnitine

Neurobiology of Disease, 2005
Because hyperammonemia is thought to contribute to the pathogenesis of hepatic encephalopathy, we examined the effects of ammonia on ATP levels, neuronal morphology, and synaptic function in rat hippocampal slices.
Yukitoshi Izumi, Masayo Izumi, Mio Matsukawa, Michiyo Funatsu, Charles F. Zorumski   +4 more
doaj   +1 more source

A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus [PDF]

, 2002
Many forms of long-lasting behavioral and synaptic plasticity require the synthesis of new proteins. For example, long-term potentiation (LTIP) that endures for more than an hour requires both transcription and translation.
Gingras, Anne-Claude, Kang, Hyejin, Reis, Gerald, Schuman, Erin M., Sonenberg, Nahum, Tang, Shao Jun   +5 more
core  

Enhanced Switching Performance in Single‐Crystalline PbTiO3 Ferroelectric Memristors for Replicating Synaptic Plasticity

Advanced Functional Materials, EarlyView.
This study demonstrated single‐crystalline PbTiO3‐based memristors with atomically sharp interfaces, well‐ordered lattices, and minimal lattice mismatch. The devices exhibited an ON/OFF ratio exceeding 105, high stability, and rich resistance‐state modulation.
Haining Li, Zhiqiang Liao, Risa Kataoka, Md Sarker Shamim, Takeshi Kijima, Hiroyasu Yamahara, Hitoshi Tabata, Munetoshi Seki   +7 more
wiley   +1 more source

Stress time-dependently influences the acquisition and retrieval of unrelated information by producing a memory of its own

Frontiers in Psychology, 2015
Stress induces several temporally-guided waves of psychobiological responses that differentially influence learning and memory. One way to understand how the temporal dynamics of stress influence these cognitive processes is to consider stress, itself ...
Chelsea E Cadle, Phillip R Zoladz
doaj   +1 more source

Capsaicin-sensitive C- and A-fibre nociceptors control long-term potentiation-like pain amplification in humans.

Brain : a journal of neurology, 2015
Long-term potentiation in the spinal dorsal horn requires peptidergic C-fibre activation in animals. Perceptual correlates of long-term potentiation following high-frequency electrical stimulation in humans include increased sensitivity to electrical ...
Florian Henrich, W. Magerl, T. Klein, W. Greffrath, R. Treede   +4 more
semanticscholar   +1 more source