Results 81 to 90 of about 82,808 (286)

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu   +9 more
wiley   +1 more source

Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

open access: yesFrontiers in Pharmacology, 2019
Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic transmission represent the principal experimental models underlying learning and memory.
Dalila Mango   +7 more
doaj   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

open access: yesAdvanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour   +11 more
wiley   +1 more source

The role of astrocytic aquaporin-4 in synaptic plasticity and learning and memory

open access: yesFrontiers in Integrative Neuroscience, 2016
Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the central nervous system. AQP4 is widely expressed throughout the brain, especially at the blood-brain barrier where AQP4 is highly polarized to astrocytic foot processes ...
Jenny I. Szu, Devin K. Binder
doaj   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

open access: yesAdvanced Healthcare Materials, EarlyView.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang   +7 more
wiley   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow   +6 more
wiley   +1 more source

Comparing the Efficacy of Escitalopram with and without Crocin in Restoring I/O Functions and LTP within the Hippocampal CA1 Region of Stressed Rats

open access: yesAdvanced Biomedical Research
Background: Escitalopram, a pharmacological compound, and crocin, the active compound of saffron, influence brain functions and serotonin levels. This study examined the efficacy of escitalopram with and without crocin in restoring the input-output (I/O)
Mehran Joodaki   +2 more
doaj   +1 more source

Revisiting Ferroelectric‐Gated Phototransistors: A Tripartite Synapse‐Inspired Approach to In‐Sensor Image Processing

open access: yesAdvanced Materials, EarlyView.
A ferroelectric‐gated phototransistor (FGPT) enables linear and multilevel modulation of photoconductance through partial polarization switching and photogating effects. The device achieves photonic non‐volatility over a 153 dB dynamic range and performs in‐sensor processing under unstructured illumination, demonstrating enhanced face recognition ...
Yubin Lee   +13 more
wiley   +1 more source

Neuraminidase Inhibition Primes Short-Term Depression and Suppresses Long-Term Potentiation of Synaptic Transmission in the Rat Hippocampus [PDF]

open access: gold, 2015
Аліна Савотченко   +6 more
openalex   +1 more source

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