Abstract Book for the 27th Congress of the European Hematology Association
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
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Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control [PDF]
BACKGROUND: Ichthyophthirius multifiliis, commonly known as Ich, is a highly pathogenic ciliate responsible for 'white spot', a disease causing significant economic losses to the global aquaculture industry.
Asai, David J +28 more
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Jixin Dai,1 Bing Wang,2 Yueming Zhao,1 Xuerong Zuo,1 Hongxia Cui,1 Xi Chen,2 Xianhong Liu1 1Department of Oncology, Jilin Cancer Hospital, Changchun, Jilin 130000, People’s Republic of China; 2Department of Radiotherapy, Jilin Cancer Hospital ...
Dai J +6 more
doaj
RNA Binding to CBP Stimulates Histone Acetylation and Transcription [PDF]
CBP/p300 are transcription co-activators whose binding is a signature of enhancers, cis-regulatory elements that control patterns of gene expression in multicellular organisms. Active enhancers produce bi-directional enhancer RNAs (eRNAs) and display CBP/
Bailey +82 more
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Non-coding RNAs in preeclampsia—molecular mechanisms and diagnostic potential [PDF]
Preeclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality worldwide. Defects in trophoblast invasion, differentiation of extravillous trophoblasts and spiral artery remodeling are key factors in PE development. Currently there
Antonić, Tamara +8 more
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AtNPF2.5 modulates chloride (Cl -bar) efflux from roots of Arabidopsis thaliana [PDF]
The accumulation of high concentrations of chloride (Cl(-)) in leaves can adversely affect plant growth. When comparing different varieties of the same Cl(-) sensitive plant species those that exclude relatively more Cl(-) from their shoots tend to ...
Gilliham, M. +8 more
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Whole-exome analysis in osteosarcoma to identify a personalized therapy [PDF]
Osteosarcoma is the most common pediatric primary non-hematopoietic bone tumor. Survival of these young patients is related to the response to chemotherapy and development of metastases.
Aretini, Paolo +13 more
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The transcriptome of Candida albicans mitochondria and the evolution of organellar transcription units in yeasts. [PDF]
BACKGROUND Yeasts show remarkable variation in the organization of their mitochondrial genomes, yet there is little experimental data on organellar gene expression outside few model species.
Drzewicka, Katarzyna +4 more
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Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]
Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J. +14 more
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Abstract Three types of highly promising small RNA therapeutics, namely, small interfering RNAs (siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs), offer advantages over small‐molecule drugs. These small RNAs can target any gene product, opening up new avenues of effective and safe therapeutic approaches for a wide ...
Zoltán Bereczki +14 more
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