Results 31 to 40 of about 18,982,338 (136)

Post-Transcriptional Regulation through Long Non-Coding RNAs (lncRNAs)

open access: yes, 2021
The discovery of thousands of non-coding RNAs (ncRNAs) pervasively transcribed from the eukaryotic genome has revolutionized the “central dogma” of biology and shifted the attention on the role of RNAs as regulatory molecules, more than simply ...
Giuseppina Pisignano, Michael Ladomery
core   +1 more source

Mitigating off‐target effects of small RNAs: conventional approaches, network theory and artificial intelligence

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 2, Page 340-379, January 2025.
Abstract Three types of highly promising small RNA therapeutics, namely, small interfering RNAs (siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs), offer advantages over small‐molecule drugs. These small RNAs can target any gene product, opening up new avenues of effective and safe therapeutic approaches for a wide ...
Zoltán Bereczki   +14 more
wiley   +1 more source

Acknowledgement to Reviewers of Non-Coding RNA in 2016

open access: yes, 2017
The editors of Non‐Coding RNA would like to express their sincere gratitude to the following  reviewers for assessing manuscripts in 2016.[...
Non-Coding RNA Editorial Office
core   +1 more source

MALAT1 Long Non-Coding RNA: Functional Implications

open access: yes, 2020
The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
Disha Aggarwal   +2 more
core   +1 more source

Differential Allelic Expression among Long Non-Coding RNAs

open access: yes, 2021
Long non-coding RNAs (lncRNA) comprise a diverse group of non-protein-coding RNAs >200 bp in length that are involved in various normal cellular processes and disease states, and can affect coding gene expression through mechanisms in cis or in trans ...
Paul T. Spellman   +2 more
core   +1 more source

Besides Pathology: Long Non-Coding RNA in Cell and Tissue Homeostasis

open access: yes, 2018
A significant proportion of mammalian genomes corresponds to genes that transcribe long non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning the roles played by lncRNAs in different biological processes has increased ...
Danielle Malheiros   +7 more
core   +1 more source

Non-coding RNA and transcriptional regulation in CD4 T cell lineages [PDF]

open access: yes, 2015
CD4 T cell lineage choice epitomises the ability of the immune system to become tailored to a specific threat and provides a framework for understanding the mechanisms behind cell specification.
Evans, CM
core  

Prediction of Sinorhizobium meliloti sRNA genes and experimental detection in strain 2011 [PDF]

open access: yes, 2008
Valverde C, Livny J, Schlüter J-P, Reinkensmeier J, Becker A, Parisi G. Prediction of Sinorhizobium meliloti sRNA genes and experimental detection in strain 2011. BMC Genomics.
Schlüter, Jan-Philip   +11 more
core   +1 more source

Long Non-Coding RNA Signatures in Lymphopoiesis and Lymphoid Malignancies

open access: yes, 2023
Lymphoid cells play a critical role in the immune system, which includes three subgroups of T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in lymphopoiesis has revolutionized our understanding of the regulatory ...
Mahdi Zavvar   +8 more
core   +1 more source

Long Non-Coding RNA Levels Are Modulated in Schistosoma mansoni following In Vivo Praziquantel Exposure

open access: yes
Schistosomiasis is a disease caused by trematodes of the genus Schistosoma that affects over 200 million people worldwide. For decades, praziquantel (PZQ) has been the only available drug to treat the disease. Despite recent discoveries that identified a
Murilo Sena Amaral   +5 more
core   +1 more source

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