Results 31 to 40 of about 20,310,635 (136)
British Journal of Pharmacology, Volume 182, Issue 2, Page 340-379, January 2025.Abstract Three types of highly promising small RNA therapeutics, namely, small interfering RNAs (siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs), offer advantages over small‐molecule drugs. These small RNAs can target any gene product, opening up new avenues of effective and safe therapeutic approaches for a wide ...
Zoltán Bereczki +14 more
wiley +1 more source
Acknowledgment to Reviewers of Non-Coding RNA in 2020
, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Non-Coding RNA maintains its standards for the high quality of its published papers [...
Non-Coding RNA Editorial Office +1 more
core +1 more source
Besides Pathology: Long Non-Coding RNA in Cell and Tissue Homeostasis
, 2018 A significant proportion of mammalian genomes corresponds to genes that transcribe long non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning the roles played by lncRNAs in different biological processes has increased ...
Danielle Malheiros +7 more
core +1 more source
Transposable element insertions in long intergenic non-coding RNA genes [PDF]
, 2015 Transposable elements (TE) are abundant in mammalian genomes and appear to have contributed to the evolution of their hosts by providing novel regulatory or coding sequences. We analyzed different regions of long intergenic non-coding RNA (lincRNA) genes
David eManagadze +18 more
core +1 more source
, 2023 Number of differentially expressed features in each datatype (PcG: Protein-coding genes, lnc RNA: Long non-coding RNA, miRNA: micro-RNA).
Sudhanshu Shukla (408600) +2 more
core +1 more source
Non-Coding RNAs in Breast Cancer: Intracellular and Intercellular Communication
, 2018 Non-coding RNAs (ncRNAs) are regulators of intracellular and intercellular signaling in breast cancer. ncRNAs modulate intracellular signaling to control diverse cellular processes, including levels and activity of estrogen receptor α (ERα ...
Carolyn M. Klinge, Carolyn M. Klinge
core +1 more source
Ubiquitous selective constraints in the Drosophila genome revealed by a genome-wide interspecies comparison [PDF]
, 2006 Non-coding DNA comprises ∼80% of the euchromatic portion of the Drosophila melanogaster genome. Non-coding sequences are known to contain functionally important elements controlling gene expression, but the proportion of sites that are selectively ...
Keightley, Peter, Halligan, Daniel
core +1 more source
Intergenic long non-coding RNA vs mRNA pairs.
, 2023 Long non-coding (lnc)RNAs are a class of eukaryotic RNA that do not code for protein and are linked with transcriptional regulation, amongst a myriad of other functions.
Russell M. Morphew (162753) +6 more
core +1 more source
The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm
, 2022 Besides transcription, RNA decay accounts for a large proportion of regulated gene expression and is paramount for cellular functions. Classical RNA surveillance pathways, like nonsense-mediated decay (NMD), are also implicated in the turnover of non ...
Jaé, Nicolas Christopher +28 more
core +1 more source
Schistosomiasis is a disease caused by trematodes of the genus Schistosoma that affects over 200 million people worldwide. For decades, praziquantel (PZQ) has been the only available drug to treat the disease. Despite recent discoveries that identified a
Murilo Sena Amaral +5 more
core +1 more source