Results 221 to 230 of about 720,765 (309)

Long non-coding RNA transcripts in Mycobacterium tuberculosis-host interactions. [PDF]

open access: yesNoncoding RNA Res
Vijayaraghavan M   +2 more
europepmc   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu   +13 more
wiley   +1 more source

Erratum To: Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

open access: yesEMBO Molecular Medicine, 2022
Jin Yao   +15 more
doaj   +1 more source

Ultralow‐Dimensionality Reduction for Identifying Critical Transitions by Spatial‐Temporal PCA

open access: yesAdvanced Science, EarlyView.
The proposed spatial‐temporal principal component analysis (stPCA) method analytically reduces high‐dimensional time‐series data to a single latent variable by transforming spatial information into temporal dynamics. By preserving the temporal properties of the original data, stPCA effectively identifies critical transitions and tipping points.
Pei Chen   +6 more
wiley   +1 more source

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong   +13 more
wiley   +1 more source

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

open access: yesAdvanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang   +6 more
wiley   +1 more source

Development of a T cell engaging bispecific antibody targeting long non-coding RNA PVT1. [PDF]

open access: yesCancer Immunol Immunother
Kato H   +12 more
europepmc   +1 more source

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