Results 241 to 250 of about 720,765 (309)

Long non‐coding RNA MILNR1 retards colorectal cancer growth by inhibiting c‐Myc

open access: yesCancer Communications, 2020
Hao Gu   +9 more
doaj   +1 more source

The GhWL1‐GhH1‐GhGA2OX1 Transcriptional Module Regulates Cotton Leaf Morphology

open access: yesAdvanced Science, EarlyView.
This study identified GhWL1 as a key gene involved in regulating leaf development through analysis of a T‐DNA insertion mutant. The GhWL1‐GhH1 complex is shown to positively regulate GhGA2OX1 by directly binding to its promoter, thereby establishing the GhWL1‐GhH1‐GhGA2OX1 module as a critical pathway in leaf development.
Jingjing Zhan   +12 more
wiley   +1 more source

Long non-coding RNA CYTOR promotes the progression of melanoma <i>via</i> the miR-485-5p/GPI axis. [PDF]

open access: yesPeerJ
Lu H   +10 more
europepmc   +1 more source

NF2 is Essential for Human Endoderm Development

open access: yesAdvanced Science, EarlyView.
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong   +5 more
wiley   +1 more source

Significance of long non‐coding RNA AGPG for the metabolism of esophageal cancer

open access: yesCancer Communications, 2020
Rebecca Elizabeth Vargas, Wenqi Wang
doaj   +1 more source

TblncRNA-23, a long non-coding RNA transcribed by RNA polymerase I, regulates developmental changes in Trypanosoma brucei. [PDF]

open access: yesNat Commun
Galili-Kostin B   +10 more
europepmc   +1 more source

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

open access: yesAdvanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang   +4 more
wiley   +1 more source

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