Results 251 to 260 of about 720,765 (309)

Long non-coding RNA AC133552.2: biomarker and therapeutic target in osteosarcoma via PANoptosis gene screening. [PDF]

Sci Rep
Zhao W, Wang Y, Zhu J, Arya S, Huang G, Li S, Chen Q, Liu X, Yuan J, Jia J.   +9 more
europepmc   +1 more source

Caspase‐6/Gasdermin C‐Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2‐Dependent Recruitment of Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
Hypoxic and low‐glucose conditions in tumor tissues trigger colorectal tumor cell pyroptosis via sequential activation of the Caspase‐1/Caspase‐6/GSDMC axis. High mobility group box 1 (HMGB1), released from GSDMC‐mediated pyroptotic tumor cells, upregulates CXCL2 expression in adjacent tumor cells, thereby recruiting myeloid‐derived suppressor cells ...
Hanchao Gao, Yikun Yao, Weilong Li, Zigan Xu, Wenjun Hu, Kewang Luo, Peishan Chen, Wanjing Shang, Shaodong Luan, Guojun Shi, Mengtao Cao, Pengfei Chen   +11 more
wiley   +1 more source

Long non-coding RNA NEAT1 promotes colorectal cancer progression via interacting with SIRT1. [PDF]

Sci Rep
Li Y, Xu Y, Yu X, Su S, Wu B, Su Y, Guo L.   +6 more
europepmc   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

Advanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang, Xudan Dou, Yongzhan Sun, Mengyao Wang, Jing Wang, Xinyi Cao, Haijie Xie, Linguo Xie, Weiping Tian, Jing Nie, Yupeng Chen, Chunyu Liu, Lirong Zhang   +12 more
wiley   +1 more source

Long Non-Coding RNA Function in Smooth Muscle Cell Plasticity and Atherosclerosis. [PDF]

Arterioscler Thromb Vasc Biol
Maegdefessel L, Fasolo F.
europepmc   +1 more source

From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis

Advanced Science, EarlyView.
This work utilizes spatial transcriptomics to map the transcriptional landscape of adenomyosis with obvious invagination structure from the invaginating site to deep lesions. By integrating with single‐cell RNA sequencing, this study elucidates the molecular features of invagination, invasion, and fibrosis, and finds the major participants and vital ...
Boyu Li, Jia Qi, Yumeng Cao, Yijing Long, Zhe Wei, Wang‐Sheng Wang, Shuanggang Hu, Yuan Wang, Qinling Zhu, Xiao Hu, Zhe Sun, Jie Zhu, Taiyang Ye, Yejie Yao, Yiwen Meng, Xuejiao Bian, Xinyi Dong, Hengyu Guan, Yunfei Huang, Yun Sun   +19 more
wiley   +1 more source

Clinical Significance and Pathogenic Mechanisms of Long Non-Coding RNA TRPM2-AS in Cancers. [PDF]

Technol Cancer Res Treat
Huang S, Li B, Chen H, Rong C, Yang Z, Zhang X.   +5 more
europepmc   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

The role of long non-coding RNA A2M-AS1 in early diagnosis and prognosis evaluation of acute myocardial infarction. [PDF]

J Cardiothorac Surg
Cao C, Hu Q, Hu X, Zhu L, Jia H, Shen Y, Chen J, Xu B, Zhang B.   +8 more
europepmc   +1 more source

Genome‐Wide Association Studies Reveal the Genetic Architecture of Ionomic Variation in Grains of Tartary Buckwheat

Advanced Science, EarlyView.
In this study, variation and genetic basis of ionome among Tartary buckwheat population are investigated, illuminating their significance in the domestication and diversification of Tartary buckwheat. And three genes (FtACA13 for Na content, FtYPQ1 for Zn content, FtNHX2 for As content) are identified with the dominant haplotypes and functional ...
Zhirong Wang, Yuqi He, Mengyu Zhao, Xiang‐Qian Liu, Hao Lin, Yaliang Shi, Kaixuan Zhang, Guijie Lei, Dili Lai, Tong Liu, Xiaoyang Peng, Jiayue He, Wei Li, Xiangru Wang, Sun‐Hee Woo, Muriel Quinet, Alisdair R. Fernie, Xin‐Yuan Huang, Meiliang Zhou   +18 more
wiley   +1 more source